2 Citations (Scopus)

Abstract

We report a case of a 61-year-old man with a history of CREST syndrome (calcinosis cutis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) who presented for evaluation of thrombocytopenia. He had evident cervical adenopathy and lymph node biopsy showed small lympphocytic lymphoma (SLL) with evident systemic adenopathy and bone marrow involvement. The patient achieved a complete remission with FCR (fludarabine/cyclophosphamide/rituximab) chemotherapy. About 30 cases of lymphomas are reported in the literature in association with systemic sclerosis. To our knowledge, there are no reports of a small lymphocytic lymphoma (SLL) in association with limited cutaneous systemic sclerosis with classic features of the CREST syndrome.

Original languageEnglish (US)
Pages (from-to)132-135
Number of pages4
JournalHematology/ Oncology and Stem Cell Therapy
Volume4
Issue number3
DOIs
StatePublished - Jan 1 2011

Fingerprint

CREST Syndrome
Systemic Scleroderma
B-Cell Chronic Lymphocytic Leukemia
Lymphoma
Esophageal Motility Disorders
Calcinosis
Telangiectasis
Raynaud Disease
Thrombocytopenia
Cyclophosphamide
Lymph Nodes
Bone Marrow
Biopsy
Drug Therapy
Skin
Lymphadenopathy

ASJC Scopus subject areas

  • Hematology
  • Oncology

Cite this

Small lymphocytic lymphoma in a patient with CREST syndrome. / William, Basem M.; Harbert, Tracey; Ganti, Apar Kishor P; Bierman, Philip Jay.

In: Hematology/ Oncology and Stem Cell Therapy, Vol. 4, No. 3, 01.01.2011, p. 132-135.

Research output: Contribution to journalArticle

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