Simultaneous measurements of pressure and voltage at the basilar membrane inform theories of amplification

Elizabeth S. Olson, Wei Dong, Stephen T Neely

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A feature of cochlear mechanics is local amplification, in which the response at a given frequency is amplified over a relatively narrow longitudinal extent of the cochlea. The basis for the place-frequency tuning of the amplifier has been explored in cochlear theories, and many models predict realistic level-dependent tuning in BM motion. Modern observations of in vivo active cochlear mechanics also include measurements of local driving pressure, and local extra-cellular voltage. These quantities have been predicted by theories of active cochlear mechanics, and thus the data provide useful modeling constraints. In particular, experimental observations argue against an amplifier that results in highly tuned and nonlinear relationships between pressure:velocity:voltage. These observations are consistent with predictions of some but not all cochlear models. Thus, simultaneous measurements of several cochlear quantities can be very useful in guiding concepts of how cochlear tuning and amplification work.

Original languageEnglish (US)
Title of host publicationWhat Fire is in Mine Ears
Subtitle of host publicationProgress in Auditory Biomechanics - Proceedings of the 11th International Mechanics of Hearing Workshop
Pages638-643
Number of pages6
DOIs
StatePublished - Dec 12 2011
Event11th International Mechanics of Hearing Workshop - What Fire is in Mine Ears: Progress in Auditory Biomechanics - Williamstown, MA, United States
Duration: Jul 16 2011Jul 22 2011

Publication series

NameAIP Conference Proceedings
Volume1403
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference11th International Mechanics of Hearing Workshop - What Fire is in Mine Ears: Progress in Auditory Biomechanics
CountryUnited States
CityWilliamstown, MA
Period7/16/117/22/11

Fingerprint

tuning
membranes
electric potential
amplifiers
cochlea
predictions

Keywords

  • basilar membrane
  • cochlea
  • cochlear amplifier

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Olson, E. S., Dong, W., & Neely, S. T. (2011). Simultaneous measurements of pressure and voltage at the basilar membrane inform theories of amplification. In What Fire is in Mine Ears: Progress in Auditory Biomechanics - Proceedings of the 11th International Mechanics of Hearing Workshop (pp. 638-643). (AIP Conference Proceedings; Vol. 1403). https://doi.org/10.1063/1.3658162

Simultaneous measurements of pressure and voltage at the basilar membrane inform theories of amplification. / Olson, Elizabeth S.; Dong, Wei; Neely, Stephen T.

What Fire is in Mine Ears: Progress in Auditory Biomechanics - Proceedings of the 11th International Mechanics of Hearing Workshop. 2011. p. 638-643 (AIP Conference Proceedings; Vol. 1403).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Olson, ES, Dong, W & Neely, ST 2011, Simultaneous measurements of pressure and voltage at the basilar membrane inform theories of amplification. in What Fire is in Mine Ears: Progress in Auditory Biomechanics - Proceedings of the 11th International Mechanics of Hearing Workshop. AIP Conference Proceedings, vol. 1403, pp. 638-643, 11th International Mechanics of Hearing Workshop - What Fire is in Mine Ears: Progress in Auditory Biomechanics, Williamstown, MA, United States, 7/16/11. https://doi.org/10.1063/1.3658162
Olson ES, Dong W, Neely ST. Simultaneous measurements of pressure and voltage at the basilar membrane inform theories of amplification. In What Fire is in Mine Ears: Progress in Auditory Biomechanics - Proceedings of the 11th International Mechanics of Hearing Workshop. 2011. p. 638-643. (AIP Conference Proceedings). https://doi.org/10.1063/1.3658162
Olson, Elizabeth S. ; Dong, Wei ; Neely, Stephen T. / Simultaneous measurements of pressure and voltage at the basilar membrane inform theories of amplification. What Fire is in Mine Ears: Progress in Auditory Biomechanics - Proceedings of the 11th International Mechanics of Hearing Workshop. 2011. pp. 638-643 (AIP Conference Proceedings).
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