Second-order conditioning detects unexpressed morphine-induced salt aversion

Rick A Bevins, Timothy A. Delzer, Michael T. Bardo

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Morphine failed to condition a salt taste aversion at a dose (15 mg/kg) sufficient to produce a robust aversion to a saccharin taste. Indeed, three different concentrations of salt (1%, 1.5%, and 2%) paired with the same morphine dose yielded no direct evidence for conditioned aversion. Yet, when a novel saccharin taste was paired in compound with the previously conditioned salt conditioned stimulus, we found evidence for a conditioning to the saccharin cue alone in three separate experiments. Control groups eliminated alternative accounts such as neophobia and differential exposure to morphine. Combined, these findings indicate that morphine conditioned a salt aversion. Although this aversion was not directly expressed, a second- order conditioning procedure was able to provide a more sensitive index of conditioning.

Original languageEnglish (US)
Pages (from-to)221-229
Number of pages9
JournalAnimal Learning and Behavior
Volume24
Issue number2
StatePublished - May 1 1996

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morphine
saccharin
Saccharin
Morphine
Salts
salts
dosage
salt concentration
Cues
Control Groups
Conditioning (Psychology)

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Animal Science and Zoology
  • Psychology(all)
  • Behavioral Neuroscience

Cite this

Second-order conditioning detects unexpressed morphine-induced salt aversion. / Bevins, Rick A; Delzer, Timothy A.; Bardo, Michael T.

In: Animal Learning and Behavior, Vol. 24, No. 2, 01.05.1996, p. 221-229.

Research output: Contribution to journalArticle

Bevins, Rick A ; Delzer, Timothy A. ; Bardo, Michael T. / Second-order conditioning detects unexpressed morphine-induced salt aversion. In: Animal Learning and Behavior. 1996 ; Vol. 24, No. 2. pp. 221-229.
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