Sclerosing inflammatory pseudotumor of the eye

Harvey S. Uy, Quan Dong Nguyen, Jean Arbour, Michel Gravel, Donald J. D'Amico, Frederick A. Jakobiec, C. Stephen Foster

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We report the clinical course and pathologic findings in a case of intraocular sclerosing inflammatory pseudotumor in a 21-year-old man. The patient initially had a unilateral right interstitial keratitis, scleritis, uveitis, ciliary body mass, and retinal detachment. Scleral and vitreous biopsy specimens revealed an inflammatory process. The eye was eventually enucleated despite therapy with high doses of prednisone and ciprofloxacin hydrochloride. Histologic examination of the globe showed nongranulomatous, acute (neutrophils) and chronic (lymphocytes and histiocytes) inflammation with proliferation of fibrous tissue within the vitreous cavity, uvea, sclera, and contiguous orbital fibroadipose tissue. The contralateral eye later developed a similar mass that resolved following aggressive and prolonged immunosuppressive therapy with retention of 20/16 visual acuity.

Original languageEnglish (US)
Pages (from-to)603-607
Number of pages5
JournalArchives of Ophthalmology
Volume119
Issue number4
DOIs
StatePublished - Jan 1 2001

Fingerprint

Plasma Cell Granuloma
Uvea
Scleritis
Ciliary Body
Sclera
Histiocytes
Keratitis
Uveitis
Retinal Detachment
Immunosuppressive Agents
Ciprofloxacin
Prednisone
Visual Acuity
Neutrophils
Lymphocytes
Inflammation
Biopsy
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Uy, H. S., Nguyen, Q. D., Arbour, J., Gravel, M., D'Amico, D. J., Jakobiec, F. A., & Foster, C. S. (2001). Sclerosing inflammatory pseudotumor of the eye. Archives of Ophthalmology, 119(4), 603-607. https://doi.org/10.1001/archopht.119.4.603

Sclerosing inflammatory pseudotumor of the eye. / Uy, Harvey S.; Nguyen, Quan Dong; Arbour, Jean; Gravel, Michel; D'Amico, Donald J.; Jakobiec, Frederick A.; Foster, C. Stephen.

In: Archives of Ophthalmology, Vol. 119, No. 4, 01.01.2001, p. 603-607.

Research output: Contribution to journalArticle

Uy, HS, Nguyen, QD, Arbour, J, Gravel, M, D'Amico, DJ, Jakobiec, FA & Foster, CS 2001, 'Sclerosing inflammatory pseudotumor of the eye', Archives of Ophthalmology, vol. 119, no. 4, pp. 603-607. https://doi.org/10.1001/archopht.119.4.603
Uy HS, Nguyen QD, Arbour J, Gravel M, D'Amico DJ, Jakobiec FA et al. Sclerosing inflammatory pseudotumor of the eye. Archives of Ophthalmology. 2001 Jan 1;119(4):603-607. https://doi.org/10.1001/archopht.119.4.603
Uy, Harvey S. ; Nguyen, Quan Dong ; Arbour, Jean ; Gravel, Michel ; D'Amico, Donald J. ; Jakobiec, Frederick A. ; Foster, C. Stephen. / Sclerosing inflammatory pseudotumor of the eye. In: Archives of Ophthalmology. 2001 ; Vol. 119, No. 4. pp. 603-607.
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