Scleral patch graft in the management of necrotizing scleritis

Quan Dong Nguyen, C. Stephen Foster

Research output: Contribution to journalReview article

33 Citations (Scopus)

Abstract

NS is a rare but devastating consequence of certain connective tissue disorders, most commonly RA. The presence of NS mandates that patients be treated with at least one immunosuppressive chemotherapeutic drug. The cure rate is high in such instances after 1 year of freedom from any evidence of recurrent inflammation. Surgical treatment through tectonic scleral and peripheral corneal grafting is rarely (although sometimes) indicated, except in instances of NS that has advanced to the point of perforation of the globe. Various graft materials can be used, including fascia lata, periosteum, split-thickness dermis, Gore-Tex (synthetic), aortic tissue, and autologous or homologous sclera. Surgical treatment alone will not solve the problem for the patient. The physician also must control the underlying immunoregulatory dysfunction that has caused the destruction initially to protect the graft and, subsequently, the patient's eye.

Original languageEnglish (US)
Pages (from-to)109-131
Number of pages23
JournalInternational Ophthalmology Clinics
Volume39
Issue number1
DOIs
StatePublished - Jan 1 1999

Fingerprint

Scleritis
Transplants
Fascia Lata
Periosteum
Sclera
Corneal Transplantation
Immunosuppressive Agents
Dermis
Connective Tissue
Inflammation
Physicians
Therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Scleral patch graft in the management of necrotizing scleritis. / Nguyen, Quan Dong; Foster, C. Stephen.

In: International Ophthalmology Clinics, Vol. 39, No. 1, 01.01.1999, p. 109-131.

Research output: Contribution to journalReview article

Nguyen, Quan Dong ; Foster, C. Stephen. / Scleral patch graft in the management of necrotizing scleritis. In: International Ophthalmology Clinics. 1999 ; Vol. 39, No. 1. pp. 109-131.
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