Safe administration of iron dextran to a patient who reacted to the test dose

Michael S. Monaghan, Gerry Glasco, Greg St.John, Robert W. Bradsher, Keith M. Olsen

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Abstract

Parenteral iron therapy is infrequently required but generally well tolerated. We present a case in which intravenous iron dextran was successfully given to a patient who had an anaphylactoid reaction to the test dose. After pretreatment with methylprednisolone, diphenhydramine, ephedrine, and dextran 1, 2 g of iron dextran were safely given over several days; pretreatment was administered only on day 1. In the rare cases in which an anaphylactic agent must be given to a patient with a history of a life-threatening reaction to the agent, pretreatment along with slow escalation of dose may allow safe administration of the offending drug.

Original languageEnglish (US)
Pages (from-to)1010-1012
Number of pages3
JournalSouthern Medical Journal
Volume87
Issue number10
DOIs
StatePublished - Oct 1994

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Monaghan, M. S., Glasco, G., St.John, G., Bradsher, R. W., & Olsen, K. M. (1994). Safe administration of iron dextran to a patient who reacted to the test dose. Southern Medical Journal, 87(10), 1010-1012. https://doi.org/10.1097/00007611-199410000-00011