Room temperature synthesis of glycerol carbonate catalyzed by N-heterocyclic carbenes

Britni Hervert, Patrick D. McCarthy, Hector Palencia

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

N-Heterocyclic carbenes were used as efficient organocatalysts for the synthesis of glycerol carbonate from glycerol and dimethyl carbonate. The reaction takes place in a liquid mixture of reactants without solvent at room temperature. It provides glycerol carbonate in high yield using 2.6-4 mol % of catalyst in a reaction period of 20-30 min.

Original languageEnglish (US)
Pages (from-to)133-136
Number of pages4
JournalTetrahedron Letters
Volume55
Issue number1
DOIs
StatePublished - Jan 1 2014

Fingerprint

Carbonates
Glycerol
Temperature
Catalysts
Liquids
carbene

Keywords

  • Dimethyl carbonate
  • Glycerol carbonate
  • N-Heterocyclic carbenes
  • Organocatalysis
  • Room temperature

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Room temperature synthesis of glycerol carbonate catalyzed by N-heterocyclic carbenes. / Hervert, Britni; McCarthy, Patrick D.; Palencia, Hector.

In: Tetrahedron Letters, Vol. 55, No. 1, 01.01.2014, p. 133-136.

Research output: Contribution to journalArticle

Hervert, Britni ; McCarthy, Patrick D. ; Palencia, Hector. / Room temperature synthesis of glycerol carbonate catalyzed by N-heterocyclic carbenes. In: Tetrahedron Letters. 2014 ; Vol. 55, No. 1. pp. 133-136.
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