Role of invasive functional assessment in surgical revascularization of coronary artery disease

Bipul Baibhav, Maheedhar Gedela, Michael Moulton, Gregory Pavlides, Vincent Pompili, Tanveer Rab, George Dangas, Deepak L. Bhatt, Aleem Siddique, Yiannis S. Chatzizisis

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In patients with stable coronary artery disease, percutaneous coronary intervention is associated with improved outcomes if the lesion is deemed significant by invasive functional assessment using fractional flow reserve. Recent studies have shown that a revascularization strategy using instantaneous wave-free ratio is noninferior to fractional flow reserve in patients with intermediate-grade stenoses. The decision to perform coronary artery bypass grafting surgery is usually based on anatomic assessment of stenosis severity by coronary angiography. The data on the role of invasive functional assessment in guiding surgical revascularization are limited. In this review, we discuss the diagnostic and prognostic significance of invasive functional assessment in patients considered for coronary artery bypass grafting. In addition, we critically discuss ongoing and future clinical trials on the role of invasive functional assessment in surgical revascularization.

Original languageEnglish (US)
Pages (from-to)1731-1739
Number of pages9
JournalCirculation
Volume137
Issue number16
DOIs
StatePublished - Jan 1 2018

Fingerprint

Coronary Artery Bypass
Coronary Artery Disease
Pathologic Constriction
Percutaneous Coronary Intervention
Coronary Angiography
Clinical Trials

Keywords

  • Coronary angiography
  • Coronary artery bypass
  • Coronary artery disease
  • Fractional flow reserve
  • Percutaneous coronary revascularization

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Role of invasive functional assessment in surgical revascularization of coronary artery disease. / Baibhav, Bipul; Gedela, Maheedhar; Moulton, Michael; Pavlides, Gregory; Pompili, Vincent; Rab, Tanveer; Dangas, George; Bhatt, Deepak L.; Siddique, Aleem; Chatzizisis, Yiannis S.

In: Circulation, Vol. 137, No. 16, 01.01.2018, p. 1731-1739.

Research output: Contribution to journalArticle

Baibhav, Bipul ; Gedela, Maheedhar ; Moulton, Michael ; Pavlides, Gregory ; Pompili, Vincent ; Rab, Tanveer ; Dangas, George ; Bhatt, Deepak L. ; Siddique, Aleem ; Chatzizisis, Yiannis S. / Role of invasive functional assessment in surgical revascularization of coronary artery disease. In: Circulation. 2018 ; Vol. 137, No. 16. pp. 1731-1739.
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AU - Dangas, George

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