Role of intramuscular receptors in the awareness of limb position

F. J. Clark, R. C. Burgess, J. W. Chapin, W. T. Lipscomb

Research output: Contribution to journalArticle

170 Citations (Scopus)

Abstract

We studied proprioception with the ankle joint and the metacarpophalangeal (MCP) joint of the index finger of humans by use of a method that could distinguish a position sense from a movement sense. The test measured how subjects' ability to detect a fixed displacement of a joint varied with the rate of joint rotation. A position sense should not depend on the speed of joint placement; therefore slow rates of movement should not degrade subjects' ability to sense joint displacements. However, in the absence of a position sense, subjects would presumably rely on movement signals that do depend on the rate of rotation, and their ability to detect displacements should decrease when rate decreases. Subjects could sense small displacements of the ankle (± 3.5°) and the MCP joint (± 2.5 ° lateral excursions) with no decrement in performance at speeds as low as 0.25 °/min for the ankle and 0.5°/min for the MCP joint (the slowest tested thus far). The findings confirm the existence of a position sense with these joints. Block of the ulnar nerve at the wrist, which paralyzes the interosseous muscles that adduct and abduct the MCP joint but presumably leaves skin and joint mechanisms unaffected, substantially impaired subjects' ability to detect the lateral excursions at slow speeds. Performance fell sharply at speeds <128°/min and leveled off at ~20% detections at speeds <4°/min. Increasing displacement to ±7° did not improve performance. Block of the common peroneal nerve at the knee, which paralyzes the ankle dorsiflexor muscles, substantially impaired subjects' ability to detect the ±3.5° displacements at slow speeds when the foot was positioned to slacken the plantarflexion muscles (which were not affected by the block). Performance fell sharply at speeds <256°/min and approached zero at speeds <16°/min. However, positioning the foot to stretch, the plantarflexor muscles restored subjects' performance to near normal. Local anesthetic injected into the MCP joint space produced no observable effect on the ability to detect either slow or fast excursions. The joint anesthesia went unnoticed by the subject. We conclude that independent and separable senses exist for limb position and limb movement and that normal position sense requires sensory inputs from the muscles.

Original languageEnglish (US)
Pages (from-to)1529-1540
Number of pages12
JournalJournal of Neurophysiology
Volume54
Issue number6
DOIs
StatePublished - Jan 1 1985

Fingerprint

Proprioception
Aptitude
Metacarpophalangeal Joint
Extremities
Joints
Muscles
Ankle
Paralysis
Foot
Peroneal Nerve
Ulnar Nerve
Ankle Joint
Local Anesthetics
Wrist
Fingers
Knee
Anesthesia
Skin

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology

Cite this

Role of intramuscular receptors in the awareness of limb position. / Clark, F. J.; Burgess, R. C.; Chapin, J. W.; Lipscomb, W. T.

In: Journal of Neurophysiology, Vol. 54, No. 6, 01.01.1985, p. 1529-1540.

Research output: Contribution to journalArticle

Clark, F. J. ; Burgess, R. C. ; Chapin, J. W. ; Lipscomb, W. T. / Role of intramuscular receptors in the awareness of limb position. In: Journal of Neurophysiology. 1985 ; Vol. 54, No. 6. pp. 1529-1540.
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