Robot-aided functional imaging: Application to a motor learning study

Hermano I. Krebs, Thomas Brashers-Krug, Scott L. Rauch, Cary R. Savage, Neville Hogan, Robert H. Rubin, Alan J. Fischman, Nathaniel M. Alpert

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

The purpose of this study was to examine the neural activity underlying an implicit motor learning task. In particular, our goals were to determine whether initial phases of procedural learning of a motor task involve areas of the brain distinct from those involved in later phases of learning the task, and what changes in neural activity coincide with performance improvement. We describe a novel integration of robotic technology with functional brain imaging and its use in this study of implicit motor learning. A portable robotic device was used to generate forces that disturbed the subjects' arm movements, thereby generating a 'virtual mechanical environment' that the subjects learned to manipulate. Positron emission tomography (PET) was used to measure indices of neural activity underlying learning of the motor task. Eight healthy, right-handed male subjects participated in the study. Results support the hypothesis that different stages of implicit learning (early and late implicit learning) occur in an orderly fashion, and that distinct neural structures may be involved in these different stages. In particular, neuroimaging results indicate that the cortico-striatal loop may play a significant role during early learning, and that the cortico-cerebellar loop may play a significant role during late learning.

Original languageEnglish (US)
Pages (from-to)59-72
Number of pages14
JournalHuman Brain Mapping
Volume6
Issue number1
DOIs
StatePublished - Mar 2 1998

Fingerprint

Learning
Robotics
Corpus Striatum
Functional Neuroimaging
Neuroimaging
Positron-Emission Tomography
Technology
Equipment and Supplies
Brain

Keywords

  • Arm movement
  • Functional imaging
  • Motor learning
  • Robot-aided

ASJC Scopus subject areas

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

Cite this

Robot-aided functional imaging : Application to a motor learning study. / Krebs, Hermano I.; Brashers-Krug, Thomas; Rauch, Scott L.; Savage, Cary R.; Hogan, Neville; Rubin, Robert H.; Fischman, Alan J.; Alpert, Nathaniel M.

In: Human Brain Mapping, Vol. 6, No. 1, 02.03.1998, p. 59-72.

Research output: Contribution to journalArticle

Krebs, HI, Brashers-Krug, T, Rauch, SL, Savage, CR, Hogan, N, Rubin, RH, Fischman, AJ & Alpert, NM 1998, 'Robot-aided functional imaging: Application to a motor learning study', Human Brain Mapping, vol. 6, no. 1, pp. 59-72. https://doi.org/10.1002/(SICI)1097-0193(1998)6:1<59::AID-HBM5>3.0.CO;2-K
Krebs, Hermano I. ; Brashers-Krug, Thomas ; Rauch, Scott L. ; Savage, Cary R. ; Hogan, Neville ; Rubin, Robert H. ; Fischman, Alan J. ; Alpert, Nathaniel M. / Robot-aided functional imaging : Application to a motor learning study. In: Human Brain Mapping. 1998 ; Vol. 6, No. 1. pp. 59-72.
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