Risk factors in HIV-associated diarrhoeal disease

The role of drinking water, medication and immune status

J. N.S. Eisenberg, T. J. Wade, S. Charles, M. Vu, A. Hubbard, C. C. Wright, Deborah A Levy, P. Jensen, J. M. Colford

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In a cross-sectional survey of 226 HIV-infected men, we examined the occurrence of diarrhoea and its relationship to drinking water consumption patterns, risk behaviours; immune status and medication use. Diarrhoea was reported by 47% of the respondents. Neither drinking boiled nor filtered water was significantly associated with diarrhoea (OR = 0.5 [0.2, 1.6], 1.2 [0.6, 2.5] respectively), whereas those that drank bottled water were at risk for diarrhoea (OR = 3.0 [1.1, 7.8]). Overall, 47% always or often used at least one water treatment. Of the 37% who were very concerned about drinking water, 62% had diarrhoea, 70% always or often used at least one water treatment. An increase in CD4 count was protective only for those with a low risk of diarrhoea associated with medication (OR = 0.6 [0.5, 0.9]). A 30% attributable risk to diarrhoea was estimated for those with high medication risk compared to those with low medication risk. The significant association between concern with drinking water and diarrhoea as well as between concern with drinking water and water treatment suggests awareness that drinking water is a potential transmission pathway for diarrhoeal disease. At the same time we found that a significant portion of diarrhoea was associated with other sources not related to drinking water such as medication usage.

Original languageEnglish (US)
Pages (from-to)73-81
Number of pages9
JournalEpidemiology and Infection
Volume128
Issue number1
StatePublished - Mar 20 2002

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Drinking Water
Diarrhea
HIV
Water Purification
Drinking
CD4 Lymphocyte Count
Risk-Taking
Cross-Sectional Studies
Water

ASJC Scopus subject areas

  • Epidemiology
  • Infectious Diseases

Cite this

Eisenberg, J. N. S., Wade, T. J., Charles, S., Vu, M., Hubbard, A., Wright, C. C., ... Colford, J. M. (2002). Risk factors in HIV-associated diarrhoeal disease: The role of drinking water, medication and immune status. Epidemiology and Infection, 128(1), 73-81.

Risk factors in HIV-associated diarrhoeal disease : The role of drinking water, medication and immune status. / Eisenberg, J. N.S.; Wade, T. J.; Charles, S.; Vu, M.; Hubbard, A.; Wright, C. C.; Levy, Deborah A; Jensen, P.; Colford, J. M.

In: Epidemiology and Infection, Vol. 128, No. 1, 20.03.2002, p. 73-81.

Research output: Contribution to journalArticle

Eisenberg, JNS, Wade, TJ, Charles, S, Vu, M, Hubbard, A, Wright, CC, Levy, DA, Jensen, P & Colford, JM 2002, 'Risk factors in HIV-associated diarrhoeal disease: The role of drinking water, medication and immune status', Epidemiology and Infection, vol. 128, no. 1, pp. 73-81.
Eisenberg JNS, Wade TJ, Charles S, Vu M, Hubbard A, Wright CC et al. Risk factors in HIV-associated diarrhoeal disease: The role of drinking water, medication and immune status. Epidemiology and Infection. 2002 Mar 20;128(1):73-81.
Eisenberg, J. N.S. ; Wade, T. J. ; Charles, S. ; Vu, M. ; Hubbard, A. ; Wright, C. C. ; Levy, Deborah A ; Jensen, P. ; Colford, J. M. / Risk factors in HIV-associated diarrhoeal disease : The role of drinking water, medication and immune status. In: Epidemiology and Infection. 2002 ; Vol. 128, No. 1. pp. 73-81.
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