Rhabdomyolysis and myoglobinemia in neonates

J. W. Kasik, M. P. Leuschen, David Lloyd Bolam, R. M. Nelson

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Serial myoglobin determinations were made in 20 neonates during the first week of life to determine whether birth asphyxia results in ischemic damage to muscle with the subsequent pathologic release of myoglobin. Serum myoglobin values were significantly elevated in asphyxiated infants compared with control infants. High myoglobin values correlated with a longer duration of oliguria in the neonatal intensive care unit population. The value of urine dipstick testing for myoglobinuria screening was also evaluated. Infants with elevated myoglobin values were more likely to have a strongly positive urine dipstick for occult blood in the first 48 hours of life. These data suggest that ischemic damage to muscle with pathologic release of myoglobin occurs in the neonatal period and that urine dipstick testing provides a reasonable screening examination for myoglobinuria.

Original languageEnglish (US)
Pages (from-to)255-258
Number of pages4
JournalPediatrics
Volume76
Issue number2
StatePublished - Jan 1 1985

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Rhabdomyolysis
Myoglobin
Newborn Infant
Myoglobinuria
Urine
Oliguria
Muscles
Occult Blood
Asphyxia
Neonatal Intensive Care Units
Parturition
Serum
Population

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Kasik, J. W., Leuschen, M. P., Bolam, D. L., & Nelson, R. M. (1985). Rhabdomyolysis and myoglobinemia in neonates. Pediatrics, 76(2), 255-258.

Rhabdomyolysis and myoglobinemia in neonates. / Kasik, J. W.; Leuschen, M. P.; Bolam, David Lloyd; Nelson, R. M.

In: Pediatrics, Vol. 76, No. 2, 01.01.1985, p. 255-258.

Research output: Contribution to journalArticle

Kasik, JW, Leuschen, MP, Bolam, DL & Nelson, RM 1985, 'Rhabdomyolysis and myoglobinemia in neonates', Pediatrics, vol. 76, no. 2, pp. 255-258.
Kasik JW, Leuschen MP, Bolam DL, Nelson RM. Rhabdomyolysis and myoglobinemia in neonates. Pediatrics. 1985 Jan 1;76(2):255-258.
Kasik, J. W. ; Leuschen, M. P. ; Bolam, David Lloyd ; Nelson, R. M. / Rhabdomyolysis and myoglobinemia in neonates. In: Pediatrics. 1985 ; Vol. 76, No. 2. pp. 255-258.
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