RETRACTED ARTICLE: Finite element analysis of stent deployment in a stenotic artery and their interactions

Shijia Zhao, Linxia Gu, Stacey R. Froemming, James M Hammel, Haili Lang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this study, a nonlinear finite element analysis was implemented on the balloon-expandable stent deployment in stenotic artery with asymmetric plaque to investigate the stentstenotic artery interaction. Uniform pressure loading was applied onto the inner surface of stent to expand it. The result showed that the stent restores the patency of the stenotic artery lumen; however, non-uniform expansion (i.e. dogbone shape) was observed on stent, which indicates a possibility of the injury to arterial wall at the ends of stent. The stress on arterial wall induced by stent expansion is higher than blood pressure-induced stress, which may initiate the proliferation of smooth muscle cells and lead to the restenosis. The stent design was alternated by increasing the thickness of distal strut. With this improved design, the dogboning effect was alleviated dramatically and stress level on arterial wall was also decreased. This FEM work provided a better understanding of the coronary stenting and its effect on the arterial response from biomechanical view, which can facilitate new stent design.

Original languageEnglish (US)
Title of host publication5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011
PublisherIEEE Computer Society
ISBN (Print)9781424450893
DOIs
StatePublished - Jan 1 2011

Publication series

Name5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011

Fingerprint

Finite Element Analysis
Stents
Arteries
Finite element method
Struts
Balloons
Blood pressure
Smooth Muscle Myocytes
Muscle
Cells
Hypertension
Pressure
Wounds and Injuries

Keywords

  • Finite element analysis
  • Restenosis
  • Stent
  • Stent-stenotic artery interaction
  • Stress

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

Cite this

Zhao, S., Gu, L., Froemming, S. R., Hammel, J. M., & Lang, H. (2011). RETRACTED ARTICLE: Finite element analysis of stent deployment in a stenotic artery and their interactions. In 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011 [5780291] (5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011). IEEE Computer Society. https://doi.org/10.1109/icbbe.2011.5780291

RETRACTED ARTICLE : Finite element analysis of stent deployment in a stenotic artery and their interactions. / Zhao, Shijia; Gu, Linxia; Froemming, Stacey R.; Hammel, James M; Lang, Haili.

5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011. IEEE Computer Society, 2011. 5780291 (5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zhao, S, Gu, L, Froemming, SR, Hammel, JM & Lang, H 2011, RETRACTED ARTICLE: Finite element analysis of stent deployment in a stenotic artery and their interactions. in 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011., 5780291, 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011, IEEE Computer Society. https://doi.org/10.1109/icbbe.2011.5780291
Zhao S, Gu L, Froemming SR, Hammel JM, Lang H. RETRACTED ARTICLE: Finite element analysis of stent deployment in a stenotic artery and their interactions. In 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011. IEEE Computer Society. 2011. 5780291. (5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011). https://doi.org/10.1109/icbbe.2011.5780291
Zhao, Shijia ; Gu, Linxia ; Froemming, Stacey R. ; Hammel, James M ; Lang, Haili. / RETRACTED ARTICLE : Finite element analysis of stent deployment in a stenotic artery and their interactions. 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011. IEEE Computer Society, 2011. (5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011).
@inproceedings{fa04c68af2b7481588f7b59f970ea804,
title = "RETRACTED ARTICLE: Finite element analysis of stent deployment in a stenotic artery and their interactions",
abstract = "In this study, a nonlinear finite element analysis was implemented on the balloon-expandable stent deployment in stenotic artery with asymmetric plaque to investigate the stentstenotic artery interaction. Uniform pressure loading was applied onto the inner surface of stent to expand it. The result showed that the stent restores the patency of the stenotic artery lumen; however, non-uniform expansion (i.e. dogbone shape) was observed on stent, which indicates a possibility of the injury to arterial wall at the ends of stent. The stress on arterial wall induced by stent expansion is higher than blood pressure-induced stress, which may initiate the proliferation of smooth muscle cells and lead to the restenosis. The stent design was alternated by increasing the thickness of distal strut. With this improved design, the dogboning effect was alleviated dramatically and stress level on arterial wall was also decreased. This FEM work provided a better understanding of the coronary stenting and its effect on the arterial response from biomechanical view, which can facilitate new stent design.",
keywords = "Finite element analysis, Restenosis, Stent, Stent-stenotic artery interaction, Stress",
author = "Shijia Zhao and Linxia Gu and Froemming, {Stacey R.} and Hammel, {James M} and Haili Lang",
year = "2011",
month = "1",
day = "1",
doi = "10.1109/icbbe.2011.5780291",
language = "English (US)",
isbn = "9781424450893",
series = "5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011",
publisher = "IEEE Computer Society",
booktitle = "5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011",

}

TY - GEN

T1 - RETRACTED ARTICLE

T2 - Finite element analysis of stent deployment in a stenotic artery and their interactions

AU - Zhao, Shijia

AU - Gu, Linxia

AU - Froemming, Stacey R.

AU - Hammel, James M

AU - Lang, Haili

PY - 2011/1/1

Y1 - 2011/1/1

N2 - In this study, a nonlinear finite element analysis was implemented on the balloon-expandable stent deployment in stenotic artery with asymmetric plaque to investigate the stentstenotic artery interaction. Uniform pressure loading was applied onto the inner surface of stent to expand it. The result showed that the stent restores the patency of the stenotic artery lumen; however, non-uniform expansion (i.e. dogbone shape) was observed on stent, which indicates a possibility of the injury to arterial wall at the ends of stent. The stress on arterial wall induced by stent expansion is higher than blood pressure-induced stress, which may initiate the proliferation of smooth muscle cells and lead to the restenosis. The stent design was alternated by increasing the thickness of distal strut. With this improved design, the dogboning effect was alleviated dramatically and stress level on arterial wall was also decreased. This FEM work provided a better understanding of the coronary stenting and its effect on the arterial response from biomechanical view, which can facilitate new stent design.

AB - In this study, a nonlinear finite element analysis was implemented on the balloon-expandable stent deployment in stenotic artery with asymmetric plaque to investigate the stentstenotic artery interaction. Uniform pressure loading was applied onto the inner surface of stent to expand it. The result showed that the stent restores the patency of the stenotic artery lumen; however, non-uniform expansion (i.e. dogbone shape) was observed on stent, which indicates a possibility of the injury to arterial wall at the ends of stent. The stress on arterial wall induced by stent expansion is higher than blood pressure-induced stress, which may initiate the proliferation of smooth muscle cells and lead to the restenosis. The stent design was alternated by increasing the thickness of distal strut. With this improved design, the dogboning effect was alleviated dramatically and stress level on arterial wall was also decreased. This FEM work provided a better understanding of the coronary stenting and its effect on the arterial response from biomechanical view, which can facilitate new stent design.

KW - Finite element analysis

KW - Restenosis

KW - Stent

KW - Stent-stenotic artery interaction

KW - Stress

UR - http://www.scopus.com/inward/record.url?scp=79960140266&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960140266&partnerID=8YFLogxK

U2 - 10.1109/icbbe.2011.5780291

DO - 10.1109/icbbe.2011.5780291

M3 - Conference contribution

AN - SCOPUS:79960140266

SN - 9781424450893

T3 - 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011

BT - 5th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2011

PB - IEEE Computer Society

ER -