Results with the mustard operation in simple transposition of the great arteries. 1963-1985

G. A. Trusler, W. G. Williams, K. F. Duncan, P. S. Hesslein, L. N. Benson, R. M. Freedom, T. Izukawa, P. M. Olley

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

From May 1963 to December 1985, 329 infants and children underwent repair of simple transposition of the great arteries (TGA) using Mustard's technique. To assess improvement, the patients were separated into two groups by date of operation: Group I, May 1963 to December 1973 (N = 106), and Group II, January 1974 to December 1985 (N = 223). The operative mortality was 11 (10.4%) in Group I and two (0.9%) in Group II. The 10-year actuarial survival rate was 73.4% in Group I and 93.7% in Group II. Baffle complications, similar in both groups, were identified in 81 patients; 19 were major, causing death or requiring reoperation. By latest electrocardiogram, 21 of 45 (46.7%) of Group I patients and 129 of 180 (71.7%) of Group II patients were in normal sinus rhythm. Late ambulatory electrocardiography, however, revealed that a majority of patients had sinus node dysfunction or other dysrhythmias. Right ventricular (RV) angiography revealed definite diminution of RV contractility in 14 (11%) of 126 children. At late follow-up, 113 of 148 (76%) children were in New York Heart Association (NYHA) Class I and 35 of 148 (24%) were in NYHA Class II. Firty-five (21%) patients were on cardiac medication chiefly for dysrhythmia management. There has been significant improvement in the early and late mortality with the Mustard operation, and serious baffle complications are infrequent. Dysrhythmias continue to be a major problem but the surviving patients are clinically well and relatively few have significant RV dysfunction.

Original languageEnglish (US)
Pages (from-to)251-260
Number of pages10
JournalAnnals of surgery
Volume206
Issue number3
DOIs
StatePublished - Jan 1 1987

    Fingerprint

ASJC Scopus subject areas

  • Surgery

Cite this

Trusler, G. A., Williams, W. G., Duncan, K. F., Hesslein, P. S., Benson, L. N., Freedom, R. M., Izukawa, T., & Olley, P. M. (1987). Results with the mustard operation in simple transposition of the great arteries. 1963-1985. Annals of surgery, 206(3), 251-260. https://doi.org/10.1097/00000658-198709000-00003