Resolution of a hyperprolactinemia in a western lowland gorilla (Gorilla gorilla gorilla)

Jenifer Chatfield, Lily Zhang, Jacques Ramey, Todd Bowsher, Naida Loskutoff, Kortney O'Neill

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Prolactin-secreting pituitary adenomas are one of the most common causes of infertility in women. Prolactin plays an important role in lactation and is involved in producing some of the normal mammalian breeding and maternal behaviors. Elevated serum prolactin concentrations can adversely affect the reproductive cycle in females by inhibiting the normal lutenizing hormone surge that stimulates ovulation. A 17-year-old western lowland gorilla (Gorilla gorilla gorilla) presented with low fertility and hyperprolactinemia. An MRI confirmed a pituitary mass and treatment was initiated with cabergoline. Following 8 mo of treatment, mass size decreased and serum prolactin was within normal limits. The gorilla began to engage in normal breeding behavior, and within 6 mo of completing treatment, was pregnant. Hyperprolactinemia, secondary to presumed microprolactinoma, may be more common among breeding-age gorillas than is currently diagnosed and in humans is an easily diagnosed and treatable condition.

Original languageEnglish (US)
Pages (from-to)565-566
Number of pages2
JournalJournal of Zoo and Wildlife Medicine
Volume37
Issue number4
DOIs
StatePublished - Dec 2006

Fingerprint

Gorilla gorilla
Hyperprolactinemia
prolactin
serum
lowlands
breeding
infertility
lactation
Gorilla
Prolactin
reproductive behavior
reproductive cycle
Breeding
Prolactinoma
hormone
fertility
maternal behavior
adenoma
Maternal Behavior
ovulation

Keywords

  • Adenoma
  • Cabergoline
  • Gorilla
  • Prolactin
  • Reproduction

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Chatfield, J., Zhang, L., Ramey, J., Bowsher, T., Loskutoff, N., & O'Neill, K. (2006). Resolution of a hyperprolactinemia in a western lowland gorilla (Gorilla gorilla gorilla). Journal of Zoo and Wildlife Medicine, 37(4), 565-566. https://doi.org/10.1638/06-050.1

Resolution of a hyperprolactinemia in a western lowland gorilla (Gorilla gorilla gorilla). / Chatfield, Jenifer; Zhang, Lily; Ramey, Jacques; Bowsher, Todd; Loskutoff, Naida; O'Neill, Kortney.

In: Journal of Zoo and Wildlife Medicine, Vol. 37, No. 4, 12.2006, p. 565-566.

Research output: Contribution to journalArticle

Chatfield, J, Zhang, L, Ramey, J, Bowsher, T, Loskutoff, N & O'Neill, K 2006, 'Resolution of a hyperprolactinemia in a western lowland gorilla (Gorilla gorilla gorilla)', Journal of Zoo and Wildlife Medicine, vol. 37, no. 4, pp. 565-566. https://doi.org/10.1638/06-050.1
Chatfield, Jenifer ; Zhang, Lily ; Ramey, Jacques ; Bowsher, Todd ; Loskutoff, Naida ; O'Neill, Kortney. / Resolution of a hyperprolactinemia in a western lowland gorilla (Gorilla gorilla gorilla). In: Journal of Zoo and Wildlife Medicine. 2006 ; Vol. 37, No. 4. pp. 565-566.
@article{5e0f35364a604a909cc134e1a8909509,
title = "Resolution of a hyperprolactinemia in a western lowland gorilla (Gorilla gorilla gorilla)",
abstract = "Prolactin-secreting pituitary adenomas are one of the most common causes of infertility in women. Prolactin plays an important role in lactation and is involved in producing some of the normal mammalian breeding and maternal behaviors. Elevated serum prolactin concentrations can adversely affect the reproductive cycle in females by inhibiting the normal lutenizing hormone surge that stimulates ovulation. A 17-year-old western lowland gorilla (Gorilla gorilla gorilla) presented with low fertility and hyperprolactinemia. An MRI confirmed a pituitary mass and treatment was initiated with cabergoline. Following 8 mo of treatment, mass size decreased and serum prolactin was within normal limits. The gorilla began to engage in normal breeding behavior, and within 6 mo of completing treatment, was pregnant. Hyperprolactinemia, secondary to presumed microprolactinoma, may be more common among breeding-age gorillas than is currently diagnosed and in humans is an easily diagnosed and treatable condition.",
keywords = "Adenoma, Cabergoline, Gorilla, Prolactin, Reproduction",
author = "Jenifer Chatfield and Lily Zhang and Jacques Ramey and Todd Bowsher and Naida Loskutoff and Kortney O'Neill",
year = "2006",
month = "12",
doi = "10.1638/06-050.1",
language = "English (US)",
volume = "37",
pages = "565--566",
journal = "Journal of Zoo and Wildlife Medicine",
issn = "1042-7260",
publisher = "American Association of Zoo Veterinarians",
number = "4",

}

TY - JOUR

T1 - Resolution of a hyperprolactinemia in a western lowland gorilla (Gorilla gorilla gorilla)

AU - Chatfield, Jenifer

AU - Zhang, Lily

AU - Ramey, Jacques

AU - Bowsher, Todd

AU - Loskutoff, Naida

AU - O'Neill, Kortney

PY - 2006/12

Y1 - 2006/12

N2 - Prolactin-secreting pituitary adenomas are one of the most common causes of infertility in women. Prolactin plays an important role in lactation and is involved in producing some of the normal mammalian breeding and maternal behaviors. Elevated serum prolactin concentrations can adversely affect the reproductive cycle in females by inhibiting the normal lutenizing hormone surge that stimulates ovulation. A 17-year-old western lowland gorilla (Gorilla gorilla gorilla) presented with low fertility and hyperprolactinemia. An MRI confirmed a pituitary mass and treatment was initiated with cabergoline. Following 8 mo of treatment, mass size decreased and serum prolactin was within normal limits. The gorilla began to engage in normal breeding behavior, and within 6 mo of completing treatment, was pregnant. Hyperprolactinemia, secondary to presumed microprolactinoma, may be more common among breeding-age gorillas than is currently diagnosed and in humans is an easily diagnosed and treatable condition.

AB - Prolactin-secreting pituitary adenomas are one of the most common causes of infertility in women. Prolactin plays an important role in lactation and is involved in producing some of the normal mammalian breeding and maternal behaviors. Elevated serum prolactin concentrations can adversely affect the reproductive cycle in females by inhibiting the normal lutenizing hormone surge that stimulates ovulation. A 17-year-old western lowland gorilla (Gorilla gorilla gorilla) presented with low fertility and hyperprolactinemia. An MRI confirmed a pituitary mass and treatment was initiated with cabergoline. Following 8 mo of treatment, mass size decreased and serum prolactin was within normal limits. The gorilla began to engage in normal breeding behavior, and within 6 mo of completing treatment, was pregnant. Hyperprolactinemia, secondary to presumed microprolactinoma, may be more common among breeding-age gorillas than is currently diagnosed and in humans is an easily diagnosed and treatable condition.

KW - Adenoma

KW - Cabergoline

KW - Gorilla

KW - Prolactin

KW - Reproduction

UR - http://www.scopus.com/inward/record.url?scp=33846141786&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846141786&partnerID=8YFLogxK

U2 - 10.1638/06-050.1

DO - 10.1638/06-050.1

M3 - Article

C2 - 17315448

AN - SCOPUS:33846141786

VL - 37

SP - 565

EP - 566

JO - Journal of Zoo and Wildlife Medicine

JF - Journal of Zoo and Wildlife Medicine

SN - 1042-7260

IS - 4

ER -