Renal Cell Carcinoma Associated with TFE3 Gene Fusion in an Elderly Woman

Chad A. LaGrange, Subodh M. Lele, Stephen E. Strup

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Abstract

We present a case report of a renal cell carcinoma with TFE3 overexpression (related to TFE3 gene fusion) in a 63-year-old woman. Such tumors have been reported predominantly in children and young adults, and to our knowledge there are only 2 such cases mentioned in the literature in patients older than ours. However, we believe that this tumor may be underdiagnosed in adults owing to its similarity to clear cell (conventional) carcinoma and in some cases to papillary renal carcinoma.

Original languageEnglish (US)
Pages (from-to)590.e11-590.e12
JournalUrology
Volume70
Issue number3
DOIs
Publication statusPublished - Sep 2007

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ASJC Scopus subject areas

  • Urology

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