Release by ethanol of vitamins into rat liver perfusates

Michael Floyd Sorrell, H. Baker, A. J. Barak, O. Frank

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

In vitro perfusion of rat liver with ethanol (EtOH) causes a release of all vitamins from the liver stores, except biotin, vitamins A, E, C, and β carotene. The concentration of vitamins released from the liver by EtOH in decreasing order was B12 > B6 > pantothenate > thiamin > riboflavin > nicotinate > folate. The B12 concentration in the EtOH perfusate was high when compared with the perfusate without EtOH, implying that B12 can be rapidly released from a liver exposed to EtOH. Results also suggest that when a liver exposed to EtOH releases a vitamin from its stores, it cannot rebind the released vitamin while EtOH is being recirculated.

Original languageEnglish (US)
Pages (from-to)743-745
Number of pages3
JournalAmerican Journal of Clinical Nutrition
Volume27
Issue number7
StatePublished - Dec 1 1974

Fingerprint

Vitamins
vitamins
Ethanol
ethanol
liver
Liver
rats
Riboflavin
Niacin
Thiamine
biotin
Carotenoids
carotenes
riboflavin
Biotin
thiamin
Vitamin A
Vitamin E
Folic Acid
folic acid

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Release by ethanol of vitamins into rat liver perfusates. / Sorrell, Michael Floyd; Baker, H.; Barak, A. J.; Frank, O.

In: American Journal of Clinical Nutrition, Vol. 27, No. 7, 01.12.1974, p. 743-745.

Research output: Contribution to journalArticle

Sorrell, MF, Baker, H, Barak, AJ & Frank, O 1974, 'Release by ethanol of vitamins into rat liver perfusates', American Journal of Clinical Nutrition, vol. 27, no. 7, pp. 743-745.
Sorrell, Michael Floyd ; Baker, H. ; Barak, A. J. ; Frank, O. / Release by ethanol of vitamins into rat liver perfusates. In: American Journal of Clinical Nutrition. 1974 ; Vol. 27, No. 7. pp. 743-745.
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