Relationship between Herpesvirus ateles-associated nuclear antigen (HATNA) and the number of virus genome equivalents in HVA-carrying lymphoid lines

D. R. Johnson, S. Ohno, C. Kaschka-Dierich, B. Fleckenstein, G. Klein

Research output: Contribution to journalArticle

Abstract

A DNA-binding antigen (HATNA) was demonstrated in 7 out of 14 cell lines carrying Herpesvirus ateles (HVA) by the acid-fixed nuclear-binding technique. The seven HATNA-positive lines had means of 95, 96, 103, 177, 240, 343 and 326 virus genome equivalents/cell. For the seven HATNA-negative lines, the figures were 4, 8, 10, 33, 39, 72 and 110. This indicates a relationship between the number of HVA genome equivalents/cell and the detectability of HATNA. This association was independent of the virus producer status of the lines.

Original languageEnglish (US)
Pages (from-to)221-226
Number of pages6
JournalUnknown Journal
Volume52
Issue number2
DOIs
StatePublished - Jan 1 1981

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Rhadinovirus
Nuclear Antigens
Genome
Viruses
Antigens
Cell Line
Acids
DNA

ASJC Scopus subject areas

  • Virology

Cite this

Relationship between Herpesvirus ateles-associated nuclear antigen (HATNA) and the number of virus genome equivalents in HVA-carrying lymphoid lines. / Johnson, D. R.; Ohno, S.; Kaschka-Dierich, C.; Fleckenstein, B.; Klein, G.

In: Unknown Journal, Vol. 52, No. 2, 01.01.1981, p. 221-226.

Research output: Contribution to journalArticle

Johnson, D. R. ; Ohno, S. ; Kaschka-Dierich, C. ; Fleckenstein, B. ; Klein, G. / Relationship between Herpesvirus ateles-associated nuclear antigen (HATNA) and the number of virus genome equivalents in HVA-carrying lymphoid lines. In: Unknown Journal. 1981 ; Vol. 52, No. 2. pp. 221-226.
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