Rejection with duodenal rupture after solitary pancreas transplantation: An unusual cause of severe hematuria

R. M. Esterl, R. J. Stratta, R. J. Taylor, S. J. Radio

Research output: Contribution to journalArticle

5 Scopus citations


A common urologic complication after pancreas transplantation with bladder drainage is hematuria. However, hematuria is usually mild and self-limiting and rarely requires open surgical intervention. We report an unusual case of refractory hematuria that began 17 days after solitary pancreas transplantation due to severe rejection. The patient developed severe duodenal segment swelling with mucosal rupture that eventually required operative therapy. This case is illustrative of the diagnosis and management of gross hematuria after pancreas transplantation and demonstrates the limitations of cystoscopic techniques. This unusual complication must be considered in the differential diagnosis of refractory hematuria with pancreas allograft dysfunction and may represent a problem unique to solitary pancreas transplantation until better immunosuppressive strategies are available.

Original languageEnglish (US)
Pages (from-to)155-159
Number of pages5
JournalClinical Transplantation
Issue number3 I
StatePublished - Jan 1 1995



  • Bladder drainage
  • Cystoscopy
  • Duodenal segment
  • Duodenocystostomy
  • Hematuria
  • Immmunosuppression
  • Pancreas biopsy
  • Pancreas transplant
  • Rejection
  • Urologic complication

ASJC Scopus subject areas

  • Transplantation

Cite this