Regional variation in histopathology-specific incidence of invasive cervical cancer among Peruvian women

Christine M. Pierce Campbell, Maria P. Curado, Siobán D. Harlow, Amr S Soliman

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: To evaluate patterns of cervical cancer incidence in Peru by examining variation in 2 common histopathologic types, squamous cell carcinoma (SCC) and adenocarcinoma (ADC), and analyzing trends over time. Methods: Data on the incidence of invasive cervical cancer between 1984 and 2006 were obtained from 3 population-based cancer registries in Peru: Lima, Trujillo, and Arequipa. For each registry, data quality assessment was performed, crude and age-specific incidence was calculated, and time trends were analyzed. Results: Overall and SCC incidence varied across registries but incidence of ADC did not. Overall and SCC incidence showed significant declines in Trujillo (P < 0.05) and modest declines in Lima (P > 0.05) over time. ADC incidence showed marginally significant increases among women aged 15-29 years in Trujillo (P = 0.10) and modest increases among young women in Lima (P > 0.05). Conclusion: Population-based cancer registries were an efficient source of data for evaluating the incidence of cervical cancer once data quality had been established. Geographic and temporal variations in cervical cancer burden were documented in Peru. The trends suggest that cervical ADC is increasing among young women in urban Peru, particularly in Trujillo. We recommend supplementing current Papanicolaou test screening with complementary methods of cervical cancer control, including human papillomavirus (HPV) vaccination and HPV DNA testing.

Original languageEnglish (US)
Pages (from-to)47-51
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Volume116
Issue number1
DOIs
StatePublished - Jan 1 2012

Fingerprint

Uterine Cervical Neoplasms
Peru
Incidence
Registries
Adenocarcinoma
Squamous Cell Carcinoma
Papanicolaou Test
Information Storage and Retrieval
Population
Neoplasms
Vaccination
DNA

Keywords

  • Cervical cancer
  • Epidemiology
  • Histopathology
  • Incidence
  • Peru

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Regional variation in histopathology-specific incidence of invasive cervical cancer among Peruvian women. / Pierce Campbell, Christine M.; Curado, Maria P.; Harlow, Siobán D.; Soliman, Amr S.

In: International Journal of Gynecology and Obstetrics, Vol. 116, No. 1, 01.01.2012, p. 47-51.

Research output: Contribution to journalArticle

Pierce Campbell, Christine M. ; Curado, Maria P. ; Harlow, Siobán D. ; Soliman, Amr S. / Regional variation in histopathology-specific incidence of invasive cervical cancer among Peruvian women. In: International Journal of Gynecology and Obstetrics. 2012 ; Vol. 116, No. 1. pp. 47-51.
@article{cf145197c08441c3add9991602b97e4b,
title = "Regional variation in histopathology-specific incidence of invasive cervical cancer among Peruvian women",
abstract = "Objective: To evaluate patterns of cervical cancer incidence in Peru by examining variation in 2 common histopathologic types, squamous cell carcinoma (SCC) and adenocarcinoma (ADC), and analyzing trends over time. Methods: Data on the incidence of invasive cervical cancer between 1984 and 2006 were obtained from 3 population-based cancer registries in Peru: Lima, Trujillo, and Arequipa. For each registry, data quality assessment was performed, crude and age-specific incidence was calculated, and time trends were analyzed. Results: Overall and SCC incidence varied across registries but incidence of ADC did not. Overall and SCC incidence showed significant declines in Trujillo (P < 0.05) and modest declines in Lima (P > 0.05) over time. ADC incidence showed marginally significant increases among women aged 15-29 years in Trujillo (P = 0.10) and modest increases among young women in Lima (P > 0.05). Conclusion: Population-based cancer registries were an efficient source of data for evaluating the incidence of cervical cancer once data quality had been established. Geographic and temporal variations in cervical cancer burden were documented in Peru. The trends suggest that cervical ADC is increasing among young women in urban Peru, particularly in Trujillo. We recommend supplementing current Papanicolaou test screening with complementary methods of cervical cancer control, including human papillomavirus (HPV) vaccination and HPV DNA testing.",
keywords = "Cervical cancer, Epidemiology, Histopathology, Incidence, Peru",
author = "{Pierce Campbell}, {Christine M.} and Curado, {Maria P.} and Harlow, {Siob{\'a}n D.} and Soliman, {Amr S}",
year = "2012",
month = "1",
day = "1",
doi = "10.1016/j.ijgo.2011.08.008",
language = "English (US)",
volume = "116",
pages = "47--51",
journal = "International Journal of Gynecology and Obstetrics",
issn = "0020-7292",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Regional variation in histopathology-specific incidence of invasive cervical cancer among Peruvian women

AU - Pierce Campbell, Christine M.

AU - Curado, Maria P.

AU - Harlow, Siobán D.

AU - Soliman, Amr S

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Objective: To evaluate patterns of cervical cancer incidence in Peru by examining variation in 2 common histopathologic types, squamous cell carcinoma (SCC) and adenocarcinoma (ADC), and analyzing trends over time. Methods: Data on the incidence of invasive cervical cancer between 1984 and 2006 were obtained from 3 population-based cancer registries in Peru: Lima, Trujillo, and Arequipa. For each registry, data quality assessment was performed, crude and age-specific incidence was calculated, and time trends were analyzed. Results: Overall and SCC incidence varied across registries but incidence of ADC did not. Overall and SCC incidence showed significant declines in Trujillo (P < 0.05) and modest declines in Lima (P > 0.05) over time. ADC incidence showed marginally significant increases among women aged 15-29 years in Trujillo (P = 0.10) and modest increases among young women in Lima (P > 0.05). Conclusion: Population-based cancer registries were an efficient source of data for evaluating the incidence of cervical cancer once data quality had been established. Geographic and temporal variations in cervical cancer burden were documented in Peru. The trends suggest that cervical ADC is increasing among young women in urban Peru, particularly in Trujillo. We recommend supplementing current Papanicolaou test screening with complementary methods of cervical cancer control, including human papillomavirus (HPV) vaccination and HPV DNA testing.

AB - Objective: To evaluate patterns of cervical cancer incidence in Peru by examining variation in 2 common histopathologic types, squamous cell carcinoma (SCC) and adenocarcinoma (ADC), and analyzing trends over time. Methods: Data on the incidence of invasive cervical cancer between 1984 and 2006 were obtained from 3 population-based cancer registries in Peru: Lima, Trujillo, and Arequipa. For each registry, data quality assessment was performed, crude and age-specific incidence was calculated, and time trends were analyzed. Results: Overall and SCC incidence varied across registries but incidence of ADC did not. Overall and SCC incidence showed significant declines in Trujillo (P < 0.05) and modest declines in Lima (P > 0.05) over time. ADC incidence showed marginally significant increases among women aged 15-29 years in Trujillo (P = 0.10) and modest increases among young women in Lima (P > 0.05). Conclusion: Population-based cancer registries were an efficient source of data for evaluating the incidence of cervical cancer once data quality had been established. Geographic and temporal variations in cervical cancer burden were documented in Peru. The trends suggest that cervical ADC is increasing among young women in urban Peru, particularly in Trujillo. We recommend supplementing current Papanicolaou test screening with complementary methods of cervical cancer control, including human papillomavirus (HPV) vaccination and HPV DNA testing.

KW - Cervical cancer

KW - Epidemiology

KW - Histopathology

KW - Incidence

KW - Peru

UR - http://www.scopus.com/inward/record.url?scp=83055186631&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=83055186631&partnerID=8YFLogxK

U2 - 10.1016/j.ijgo.2011.08.008

DO - 10.1016/j.ijgo.2011.08.008

M3 - Article

VL - 116

SP - 47

EP - 51

JO - International Journal of Gynecology and Obstetrics

JF - International Journal of Gynecology and Obstetrics

SN - 0020-7292

IS - 1

ER -