Reduction in central nervous system leukemia with a pharmacokinetically derived intrathecal methotrexate dosage regimen

W. A. Bleyer, P. F. Coccia, H. N. Sather, C. Level, J. Lukens, D. J. Niebrugge, S. Siegel, P. S. Littman, S. L. Leikin, D. R. Miller

Research output: Contribution to journalArticle

83 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)317-325
Number of pages9
JournalJournal of Clinical Oncology
Volume1
Issue number5
DOIs
StatePublished - Jan 1 1983

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Drug Administration Schedule
Antineoplastic Combined Chemotherapy Protocols
Spinal Cord Neoplasms
Lymphoid Leukemia
Spinal Injections
Combined Modality Therapy
Age Factors
Acute Disease
Preschool Children
Random Allocation
Methotrexate
Brain Neoplasms
Leukemia
Central Nervous System
Clinical Trials

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Bleyer, W. A., Coccia, P. F., Sather, H. N., Level, C., Lukens, J., Niebrugge, D. J., ... Miller, D. R. (1983). Reduction in central nervous system leukemia with a pharmacokinetically derived intrathecal methotrexate dosage regimen. Journal of Clinical Oncology, 1(5), 317-325. https://doi.org/10.1200/JCO.1983.1.5.317

Reduction in central nervous system leukemia with a pharmacokinetically derived intrathecal methotrexate dosage regimen. / Bleyer, W. A.; Coccia, P. F.; Sather, H. N.; Level, C.; Lukens, J.; Niebrugge, D. J.; Siegel, S.; Littman, P. S.; Leikin, S. L.; Miller, D. R.

In: Journal of Clinical Oncology, Vol. 1, No. 5, 01.01.1983, p. 317-325.

Research output: Contribution to journalArticle

Bleyer, WA, Coccia, PF, Sather, HN, Level, C, Lukens, J, Niebrugge, DJ, Siegel, S, Littman, PS, Leikin, SL & Miller, DR 1983, 'Reduction in central nervous system leukemia with a pharmacokinetically derived intrathecal methotrexate dosage regimen', Journal of Clinical Oncology, vol. 1, no. 5, pp. 317-325. https://doi.org/10.1200/JCO.1983.1.5.317
Bleyer, W. A. ; Coccia, P. F. ; Sather, H. N. ; Level, C. ; Lukens, J. ; Niebrugge, D. J. ; Siegel, S. ; Littman, P. S. ; Leikin, S. L. ; Miller, D. R. / Reduction in central nervous system leukemia with a pharmacokinetically derived intrathecal methotrexate dosage regimen. In: Journal of Clinical Oncology. 1983 ; Vol. 1, No. 5. pp. 317-325.
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