Reciprocal connections between nucleus tractus solitarii and rostral ventrolateral medulla

Sandeep Kumar Agrawal, F. R. Calaresu

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Experiments were done to test the hypothesis that there are reciprocal connections between the nucleus of the tractus solitarius (NTS) and the rostral ventrolateral medulla (RVLM). Spontaneous activity was recorded from units in the right RVLM or NTS of urethan-anesthetized and artificially ventilated rats. Twenty-four of 42 RVLM and 12 of 21 NTS units were classified as cardiovascular because they were inhibited by baroreceptor activation and displayed a cardiac rhythm. Electrical stimulation of depressor sites in the NTS inhibited 14 and excited 10 RVLM units. Stimulation of pressor sites in the RVLM excited 10 and inhibited 2 NTS units. None of the units in the NTS or in the RVLM could be activated antidromically. These results provide evidence that there are reciprocal excitatory and inhibitory connections between NTS and RVLM and that these connections are not monosynaptic.

Original languageEnglish (US)
Pages (from-to)305-308
Number of pages4
JournalBrain Research
Volume523
Issue number2
DOIs
StatePublished - Jul 23 1990

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Solitary Nucleus
Pressoreceptors
Urethane
Electric Stimulation

Keywords

  • Arterial pressure
  • Baroreceptor reflex
  • Cardiovascular neuron
  • Monosynaptic
  • Nucleus tractus solitarii
  • Rostral ventrolateral medulla

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Reciprocal connections between nucleus tractus solitarii and rostral ventrolateral medulla. / Agrawal, Sandeep Kumar; Calaresu, F. R.

In: Brain Research, Vol. 523, No. 2, 23.07.1990, p. 305-308.

Research output: Contribution to journalArticle

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