Recent neuro-imaging findings with respect to conduct disorder, callous-unemotional traits and psychopathy

Research output: Contribution to journalReview article

Abstract

Purpose of reviewTo review recent neuro-imaging findings with respect to conduct disorder and callous-unemotional traits in childhood and comparable psychopathy in adult-hood that deepen the literature in important ways.Recent findingsRecent structural findings particularly bring clarity to the literature. First, they reinforce previous work indicating that severity of psychopathy is positively associated with extent of cavum septum pellucidum. This suggests psychopathy is associated with early neurodevelopmental disruption within limbic structures. Second, they clarify the direction of the association between conduct disorder and particularly callous-unemotional traits and white matter tract abnormalities even if it remains less transparent exactly which tracts are disrupted. However, conclusions based on recent functional imaging studies are more equivocal with inconsistencies in direction of emotional (albeit with notably more work confirming the previous reports of hypo-responsiveness in limbic regions) and reward responsiveness.SummaryThe recent data are, for the most part, consistent with a view that callous-unemotional traits/psychopathy represents an early appearing neuro-developmental disorder particularly associated with compromised emotional (limbic) functioning. However, some patients presenting with severe antisocial behavior may also show hyper-threat sensitivity, perhaps reflecting trauma exposure, and require different clinical interventions. .

Original languageEnglish (US)
Pages (from-to)45-50
Number of pages6
JournalCurrent opinion in psychiatry
Volume33
Issue number1
DOIs
StatePublished - Jan 1 2020

Fingerprint

Conduct Disorder
Septum Pellucidum
Reward
Wounds and Injuries
Direction compound
White Matter

Keywords

  • MRI
  • callous-unemotional traits
  • conduct disorder
  • psychopathic traits

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Recent neuro-imaging findings with respect to conduct disorder, callous-unemotional traits and psychopathy. / Blair, Robert James R.; Zhang, Ru.

In: Current opinion in psychiatry, Vol. 33, No. 1, 01.01.2020, p. 45-50.

Research output: Contribution to journalReview article

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