Re-irradiation for locally recurrent breast cancer

Andrew O Wahl, William Small

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Locally recurrent breast cancer occurs in 5-15 % of patients after breast conservation therapy and after mastectomy with adjuvant radiotherapy. Ipsilateral breast tumor recurrences may be salvaged with mastectomy; however, outcomes from repeat breast-conserving surgery and breast re-irradiation are promising. Chest wall recurrence generally portends a worse prognosis than in-breast local recurrences. A subset of patients may be long-term survivors in the absence of metastasis. Persistent chest wall disease can be symptomatic, and in previously irradiated patients, treatment options are limited. Experiences with chest wall re-irradiation have shown excellent response rates with acceptable late toxicity, but follow-up is limited.

Original languageEnglish (US)
Pages (from-to)213-224
Number of pages12
JournalMedical Radiology
DOIs
StatePublished - Jan 1 2017

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Thoracic Wall
Segmental Mastectomy
Mastectomy
Breast Neoplasms
Recurrence
Breast
Adjuvant Radiotherapy
Survivors
Neoplasm Metastasis
Re-Irradiation
Therapeutics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Re-irradiation for locally recurrent breast cancer. / Wahl, Andrew O; Small, William.

In: Medical Radiology, 01.01.2017, p. 213-224.

Research output: Contribution to journalArticle

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