Radiographic evidence of bronchopulmonary dysplasia in high‐risk congenital diaphragmatic hernia survivors

Albert P. Bos, Shahid M. Hussain, Frans W.J. Hazebroek, Dick Tibboel, Morteza Meradji, Jan C. Molenaar

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Congenital diaphragmatic hernia is a congenital malformation associated with pulmonary hypoplasia. It often leads to respiratory failure, requiring artificial ventilation with high inflation pressures and high percentages of oxygen. We evaluated radiographic evidence of bronchopulmonary dysplasia (BPD) in survivors, who presented with respiratory distress within 6 hours after birth, by a radiographic scoring system measuring the severity of BPD by the Toce score and the degree of pulmonary hypoplasia by the Touloukian score. Fifteen of 45 survivors (33 percent) had clinical and radiological lung disease resembling BPD. As a group they had significantly higher Touloukian and Toce scores than survivors without BPD. Morbidity expressed as the duration of artificial ventilation, supplemental oxygen, and hospital stay was much higher in the BPD group. The hypoplastic lung in infants with congenital diaphragmatic hernia appears to be as susceptible to barotrauma and pulmonary oxygen toxicity as the lungs of prematurely born infants. To what extent BPD occurring in congenital diaphragmatic hernia survivors might influence the future development of lung function is not yet known. © 1993 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)231-234
Number of pages4
JournalPediatric Pulmonology
Volume15
Issue number4
DOIs
StatePublished - Apr 1993

Fingerprint

Bronchopulmonary Dysplasia
Survivors
Lung
Oxygen
Barotrauma
Economic Inflation
Respiratory Insufficiency
Lung Diseases
Congenital Diaphragmatic Hernias
Length of Stay
Parturition
Morbidity
Pressure

Keywords

  • Touloukian score
  • pulmonary hypoplasia
  • radiographic Toce score

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Cite this

Bos, A. P., Hussain, S. M., Hazebroek, F. W. J., Tibboel, D., Meradji, M., & Molenaar, J. C. (1993). Radiographic evidence of bronchopulmonary dysplasia in high‐risk congenital diaphragmatic hernia survivors. Pediatric Pulmonology, 15(4), 231-234. https://doi.org/10.1002/ppul.1950150409

Radiographic evidence of bronchopulmonary dysplasia in high‐risk congenital diaphragmatic hernia survivors. / Bos, Albert P.; Hussain, Shahid M.; Hazebroek, Frans W.J.; Tibboel, Dick; Meradji, Morteza; Molenaar, Jan C.

In: Pediatric Pulmonology, Vol. 15, No. 4, 04.1993, p. 231-234.

Research output: Contribution to journalArticle

Bos, AP, Hussain, SM, Hazebroek, FWJ, Tibboel, D, Meradji, M & Molenaar, JC 1993, 'Radiographic evidence of bronchopulmonary dysplasia in high‐risk congenital diaphragmatic hernia survivors', Pediatric Pulmonology, vol. 15, no. 4, pp. 231-234. https://doi.org/10.1002/ppul.1950150409
Bos, Albert P. ; Hussain, Shahid M. ; Hazebroek, Frans W.J. ; Tibboel, Dick ; Meradji, Morteza ; Molenaar, Jan C. / Radiographic evidence of bronchopulmonary dysplasia in high‐risk congenital diaphragmatic hernia survivors. In: Pediatric Pulmonology. 1993 ; Vol. 15, No. 4. pp. 231-234.
@article{4390d007821849099a1ad49c80d9ce3a,
title = "Radiographic evidence of bronchopulmonary dysplasia in high‐risk congenital diaphragmatic hernia survivors",
abstract = "Congenital diaphragmatic hernia is a congenital malformation associated with pulmonary hypoplasia. It often leads to respiratory failure, requiring artificial ventilation with high inflation pressures and high percentages of oxygen. We evaluated radiographic evidence of bronchopulmonary dysplasia (BPD) in survivors, who presented with respiratory distress within 6 hours after birth, by a radiographic scoring system measuring the severity of BPD by the Toce score and the degree of pulmonary hypoplasia by the Touloukian score. Fifteen of 45 survivors (33 percent) had clinical and radiological lung disease resembling BPD. As a group they had significantly higher Touloukian and Toce scores than survivors without BPD. Morbidity expressed as the duration of artificial ventilation, supplemental oxygen, and hospital stay was much higher in the BPD group. The hypoplastic lung in infants with congenital diaphragmatic hernia appears to be as susceptible to barotrauma and pulmonary oxygen toxicity as the lungs of prematurely born infants. To what extent BPD occurring in congenital diaphragmatic hernia survivors might influence the future development of lung function is not yet known. {\circledC} 1993 Wiley‐Liss, Inc.",
keywords = "Touloukian score, pulmonary hypoplasia, radiographic Toce score",
author = "Bos, {Albert P.} and Hussain, {Shahid M.} and Hazebroek, {Frans W.J.} and Dick Tibboel and Morteza Meradji and Molenaar, {Jan C.}",
year = "1993",
month = "4",
doi = "10.1002/ppul.1950150409",
language = "English (US)",
volume = "15",
pages = "231--234",
journal = "Pediatric Pulmonology",
issn = "8755-6863",
publisher = "Wiley-Liss Inc.",
number = "4",

}

TY - JOUR

T1 - Radiographic evidence of bronchopulmonary dysplasia in high‐risk congenital diaphragmatic hernia survivors

AU - Bos, Albert P.

AU - Hussain, Shahid M.

AU - Hazebroek, Frans W.J.

AU - Tibboel, Dick

AU - Meradji, Morteza

AU - Molenaar, Jan C.

PY - 1993/4

Y1 - 1993/4

N2 - Congenital diaphragmatic hernia is a congenital malformation associated with pulmonary hypoplasia. It often leads to respiratory failure, requiring artificial ventilation with high inflation pressures and high percentages of oxygen. We evaluated radiographic evidence of bronchopulmonary dysplasia (BPD) in survivors, who presented with respiratory distress within 6 hours after birth, by a radiographic scoring system measuring the severity of BPD by the Toce score and the degree of pulmonary hypoplasia by the Touloukian score. Fifteen of 45 survivors (33 percent) had clinical and radiological lung disease resembling BPD. As a group they had significantly higher Touloukian and Toce scores than survivors without BPD. Morbidity expressed as the duration of artificial ventilation, supplemental oxygen, and hospital stay was much higher in the BPD group. The hypoplastic lung in infants with congenital diaphragmatic hernia appears to be as susceptible to barotrauma and pulmonary oxygen toxicity as the lungs of prematurely born infants. To what extent BPD occurring in congenital diaphragmatic hernia survivors might influence the future development of lung function is not yet known. © 1993 Wiley‐Liss, Inc.

AB - Congenital diaphragmatic hernia is a congenital malformation associated with pulmonary hypoplasia. It often leads to respiratory failure, requiring artificial ventilation with high inflation pressures and high percentages of oxygen. We evaluated radiographic evidence of bronchopulmonary dysplasia (BPD) in survivors, who presented with respiratory distress within 6 hours after birth, by a radiographic scoring system measuring the severity of BPD by the Toce score and the degree of pulmonary hypoplasia by the Touloukian score. Fifteen of 45 survivors (33 percent) had clinical and radiological lung disease resembling BPD. As a group they had significantly higher Touloukian and Toce scores than survivors without BPD. Morbidity expressed as the duration of artificial ventilation, supplemental oxygen, and hospital stay was much higher in the BPD group. The hypoplastic lung in infants with congenital diaphragmatic hernia appears to be as susceptible to barotrauma and pulmonary oxygen toxicity as the lungs of prematurely born infants. To what extent BPD occurring in congenital diaphragmatic hernia survivors might influence the future development of lung function is not yet known. © 1993 Wiley‐Liss, Inc.

KW - Touloukian score

KW - pulmonary hypoplasia

KW - radiographic Toce score

UR - http://www.scopus.com/inward/record.url?scp=0027587209&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027587209&partnerID=8YFLogxK

U2 - 10.1002/ppul.1950150409

DO - 10.1002/ppul.1950150409

M3 - Article

C2 - 8469576

AN - SCOPUS:0027587209

VL - 15

SP - 231

EP - 234

JO - Pediatric Pulmonology

JF - Pediatric Pulmonology

SN - 8755-6863

IS - 4

ER -