Pure red cell aplasia following ABO mismatched marrow transplantation for chronic lymphocytic leukemia: Response to antithymocyte globulin

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Pure red cell aplasia was observed in a 28 year old woman following a major ABO mismatched allogeneic bone marrow transplant for chronic lymphocytic leukemia. No evidence of red Blood cell production was observed for more than one year following transplant despite the absence of high isohemagglutinin titers. Treatment with antithymocyte globulin resulted in prompt restoration of reticulocytosis. Therapy with antithymocyte globulin should be considered in these instances when red cell aplasia follows mismatched allogeneic marrow transplantation.

Original languageEnglish (US)
Pages (from-to)169-171
Number of pages3
JournalLeukemia and Lymphoma
Issue number1-2
StatePublished - Jan 1 1993



  • ABO mismatched marrow transplantation
  • Antithymocyte globulin
  • Bone marrow transplantation
  • Chronic lymphocytic leukemia
  • Red Blood cell aplasia

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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