Pulmonary complications of transplantation

Richard A. Robbins, Anthony A. Floreani, Scott E. Buchalter, John R. Spurzem, Joseph Harold Sisson, Stephen I. Rennard

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Improved immunosuppressive regimens, advances in surgical proficiency and techniques, and improved supportive medical care have translated into dramatic increases in graft survival in organ transplantation and in patient outcome in bone marrow transplantation. Though effective immunosuppression has also led to an increase in infectious complications, several recent advances, including the development of effective surveillance protocols and antiviral therapy and the use of prophylactic antibiotics, appear to have made a significant positive impact on the management of infections and survival of transplant recipients. In addition, a clearer understanding of noninfectious pulmonary complications, such as bronchiolitis obliterans, and continued improvement in techniques for evaluating a host of posttransplant pulmonary disorders will likely further enhance posttransplant therapy and survival.

Original languageEnglish (US)
Pages (from-to)425-435
Number of pages11
JournalAnnual Review of Medicine
Volume43
DOIs
StatePublished - Jan 1 1992

Fingerprint

Transplantation (surgical)
Transplants
Lung Transplantation
Immunosuppressive Agents
Health care
Grafts
Antiviral Agents
Bone
Anti-Bacterial Agents
Bronchiolitis Obliterans
Lung
Survival
Organ Transplantation
Graft Survival
Bone Marrow Transplantation
Immunosuppression
Therapeutics
Infection
Transplant Recipients

Keywords

  • alveolar hemorrhage
  • bronchiolitis obliterans
  • bronchoalveolar lavage
  • immunocompromised host
  • pneumonia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Robbins, R. A., Floreani, A. A., Buchalter, S. E., Spurzem, J. R., Sisson, J. H., & Rennard, S. I. (1992). Pulmonary complications of transplantation. Annual Review of Medicine, 43, 425-435. https://doi.org/10.1146/annurev.me.43.020192.002233

Pulmonary complications of transplantation. / Robbins, Richard A.; Floreani, Anthony A.; Buchalter, Scott E.; Spurzem, John R.; Sisson, Joseph Harold; Rennard, Stephen I.

In: Annual Review of Medicine, Vol. 43, 01.01.1992, p. 425-435.

Research output: Contribution to journalReview article

Robbins, RA, Floreani, AA, Buchalter, SE, Spurzem, JR, Sisson, JH & Rennard, SI 1992, 'Pulmonary complications of transplantation', Annual Review of Medicine, vol. 43, pp. 425-435. https://doi.org/10.1146/annurev.me.43.020192.002233
Robbins RA, Floreani AA, Buchalter SE, Spurzem JR, Sisson JH, Rennard SI. Pulmonary complications of transplantation. Annual Review of Medicine. 1992 Jan 1;43:425-435. https://doi.org/10.1146/annurev.me.43.020192.002233
Robbins, Richard A. ; Floreani, Anthony A. ; Buchalter, Scott E. ; Spurzem, John R. ; Sisson, Joseph Harold ; Rennard, Stephen I. / Pulmonary complications of transplantation. In: Annual Review of Medicine. 1992 ; Vol. 43. pp. 425-435.
@article{c41c616b8859441aa37606df7f4507a3,
title = "Pulmonary complications of transplantation",
abstract = "Improved immunosuppressive regimens, advances in surgical proficiency and techniques, and improved supportive medical care have translated into dramatic increases in graft survival in organ transplantation and in patient outcome in bone marrow transplantation. Though effective immunosuppression has also led to an increase in infectious complications, several recent advances, including the development of effective surveillance protocols and antiviral therapy and the use of prophylactic antibiotics, appear to have made a significant positive impact on the management of infections and survival of transplant recipients. In addition, a clearer understanding of noninfectious pulmonary complications, such as bronchiolitis obliterans, and continued improvement in techniques for evaluating a host of posttransplant pulmonary disorders will likely further enhance posttransplant therapy and survival.",
keywords = "alveolar hemorrhage, bronchiolitis obliterans, bronchoalveolar lavage, immunocompromised host, pneumonia",
author = "Robbins, {Richard A.} and Floreani, {Anthony A.} and Buchalter, {Scott E.} and Spurzem, {John R.} and Sisson, {Joseph Harold} and Rennard, {Stephen I.}",
year = "1992",
month = "1",
day = "1",
doi = "10.1146/annurev.me.43.020192.002233",
language = "English (US)",
volume = "43",
pages = "425--435",
journal = "Annual Review of Medicine",
issn = "0066-4219",
publisher = "Annual Reviews Inc.",

}

TY - JOUR

T1 - Pulmonary complications of transplantation

AU - Robbins, Richard A.

AU - Floreani, Anthony A.

AU - Buchalter, Scott E.

AU - Spurzem, John R.

AU - Sisson, Joseph Harold

AU - Rennard, Stephen I.

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Improved immunosuppressive regimens, advances in surgical proficiency and techniques, and improved supportive medical care have translated into dramatic increases in graft survival in organ transplantation and in patient outcome in bone marrow transplantation. Though effective immunosuppression has also led to an increase in infectious complications, several recent advances, including the development of effective surveillance protocols and antiviral therapy and the use of prophylactic antibiotics, appear to have made a significant positive impact on the management of infections and survival of transplant recipients. In addition, a clearer understanding of noninfectious pulmonary complications, such as bronchiolitis obliterans, and continued improvement in techniques for evaluating a host of posttransplant pulmonary disorders will likely further enhance posttransplant therapy and survival.

AB - Improved immunosuppressive regimens, advances in surgical proficiency and techniques, and improved supportive medical care have translated into dramatic increases in graft survival in organ transplantation and in patient outcome in bone marrow transplantation. Though effective immunosuppression has also led to an increase in infectious complications, several recent advances, including the development of effective surveillance protocols and antiviral therapy and the use of prophylactic antibiotics, appear to have made a significant positive impact on the management of infections and survival of transplant recipients. In addition, a clearer understanding of noninfectious pulmonary complications, such as bronchiolitis obliterans, and continued improvement in techniques for evaluating a host of posttransplant pulmonary disorders will likely further enhance posttransplant therapy and survival.

KW - alveolar hemorrhage

KW - bronchiolitis obliterans

KW - bronchoalveolar lavage

KW - immunocompromised host

KW - pneumonia

UR - http://www.scopus.com/inward/record.url?scp=0026652526&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026652526&partnerID=8YFLogxK

U2 - 10.1146/annurev.me.43.020192.002233

DO - 10.1146/annurev.me.43.020192.002233

M3 - Review article

C2 - 1580600

AN - SCOPUS:0026652526

VL - 43

SP - 425

EP - 435

JO - Annual Review of Medicine

JF - Annual Review of Medicine

SN - 0066-4219

ER -