Pulmonary complications of transplantation

Richard A. Robbins, Anthony A. Floreani, Scott E. Buchalter, John R. Spurzem, Joseph Harold Sisson, Stephen I. Rennard

Research output: Contribution to journalReview article

9 Scopus citations

Abstract

Improved immunosuppressive regimens, advances in surgical proficiency and techniques, and improved supportive medical care have translated into dramatic increases in graft survival in organ transplantation and in patient outcome in bone marrow transplantation. Though effective immunosuppression has also led to an increase in infectious complications, several recent advances, including the development of effective surveillance protocols and antiviral therapy and the use of prophylactic antibiotics, appear to have made a significant positive impact on the management of infections and survival of transplant recipients. In addition, a clearer understanding of noninfectious pulmonary complications, such as bronchiolitis obliterans, and continued improvement in techniques for evaluating a host of posttransplant pulmonary disorders will likely further enhance posttransplant therapy and survival.

Original languageEnglish (US)
Pages (from-to)425-435
Number of pages11
JournalAnnual Review of Medicine
Volume43
DOIs
Publication statusPublished - Jan 1 1992

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Keywords

  • alveolar hemorrhage
  • bronchiolitis obliterans
  • bronchoalveolar lavage
  • immunocompromised host
  • pneumonia

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Robbins, R. A., Floreani, A. A., Buchalter, S. E., Spurzem, J. R., Sisson, J. H., & Rennard, S. I. (1992). Pulmonary complications of transplantation. Annual Review of Medicine, 43, 425-435. https://doi.org/10.1146/annurev.me.43.020192.002233