Psychoanatomical substrates of Bálint's syndrome

Matthew Rizzo, S. P. Vecera

Research output: Contribution to journalReview article

139 Citations (Scopus)

Abstract

Objectives: From a series of glimpses, we perceive a seamless and richly detailed visual world. Cerebral damage, however, can destroy this illusion. In the case of Bálint's syndrome, the visual world is perceived erratically, as a series of single objects. The goal of this review is to explore a range of psychological and anatomical explanations for this striking visual disorder and to propose new directions for interpreting the findings in Bálint's syndrome and related cerebral disorders of visual processing. Methods: Bálint's syndrome is reviewed in the light of current concepts and methodologies of vision research. Results: The syndrome affects visual perception (causing simultanagnosia/visual disorientation) and visual control of eye and hand movement (causing ocular apraxia and optic ataxia). Although it has been generally construed as a biparietal syndrome causing an inability to see more than one object at a time, other lesions and mechanisms are also possible. Key syndrome components are dissociable and comprise a range of disturbances that overlap the hemineglect syndrome. Inouye's observations in similar cases, beginning in 1900, antedated Bálint's initial report. Because Bálint's syndrome is not common and is difficult to assess with standard clinical tools, the literature is dominated by case reports and confounded by case selection bias, non-uniform application of operational definitions, inadequate study of basic vision, poor lesion localisation, and failure to distinguish between deficits in the acute and chronic phases of recovery. Conclusions: Studies of Bálint's syndrome have provided unique evidence on neural substrates for attention, perception, and visuomotor control. Future studies should address possible underlying psychoanatomical mechanisms at "bottom up" and "top down" levels, and should specifically consider visual working memory and attention (including object based attention) as well as systems for identification of object structure and depth from binocular stereopsis, kinetic depth, motion parallax, eye movement signals, and other cues.

Original languageEnglish (US)
Pages (from-to)162-178
Number of pages17
JournalJournal of Neurology Neurosurgery and Psychiatry
Volume72
Issue number2
DOIs
StatePublished - Jan 1 2002

Fingerprint

Vision Disorders
Eye Movements
Depth Perception
Apraxias
Confusion
Visual Perception
Selection Bias
Ataxia
Short-Term Memory
Cues
Hand
Psychology
Research
Direction compound

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Psychoanatomical substrates of Bálint's syndrome. / Rizzo, Matthew; Vecera, S. P.

In: Journal of Neurology Neurosurgery and Psychiatry, Vol. 72, No. 2, 01.01.2002, p. 162-178.

Research output: Contribution to journalReview article

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