Pseudorabies virus fast axonal transport occurs by a pUS9-independent mechanism

Gina R. Daniel, Patricia J. Sollars, Gary E. Pickard, Gregory A. Smith

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Reactivation from latency results in transmission of neurotropic herpesviruses from the nervous system to body surfaces, referred to as anterograde axonal trafficking. The virus-encoded protein pUS9 promotes axonal dissemination by sorting virus particles into axons, but whether it is also an effector of fast axonal transport within axons is unknown. To determine the role of pUS9 in anterograde trafficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.

Original languageEnglish (US)
Pages (from-to)8088-8091
Number of pages4
JournalJournal of virology
Volume89
Issue number15
DOIs
StatePublished - Jan 1 2015

    Fingerprint

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Cite this