Proton magnetic resonance spectroscopy and diffusion-weighted imaging of central nervous system Whipple disease

Jared W. Nelson, Matthew L. White, Yan Zhang, Toshio Moritani

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A 72-year-old man presented with a 6-month history of dysphagia, fatigue, 60-lb weight loss, and central nervous system (CNS) deficits. Diffusion-weighted magnetic resonance imaging (MRI) of the brain showed mildly elevated nonrestricted apparent diffusion coefficients in the middle cerebellar peduncles, and magnetic resonance spectroscopy (MRS) showed decreased N-acetylaspartate and creatine with increased choline. Diffusion-weighted MRI and MRS offer non-invasive methods to help evaluate in vivo physiologic changes of CNS involvement in Whipple disease.

Original languageEnglish (US)
Pages (from-to)320-322
Number of pages3
JournalJournal of Computer Assisted Tomography
Volume29
Issue number3
DOIs
StatePublished - May 1 2005

Fingerprint

Whipple Disease
Diffusion Magnetic Resonance Imaging
Central Nervous System Diseases
Magnetic Resonance Spectroscopy
Central Nervous System
Creatine
Deglutition Disorders
Choline
Fatigue
Weight Loss
Brain
Proton Magnetic Resonance Spectroscopy
Middle Cerebellar Peduncle
N-acetylaspartate

Keywords

  • Central nervous system infections
  • Diffusion-weighted imaging
  • Magnetic resonance spectroscopy
  • Whipple disease

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Proton magnetic resonance spectroscopy and diffusion-weighted imaging of central nervous system Whipple disease. / Nelson, Jared W.; White, Matthew L.; Zhang, Yan; Moritani, Toshio.

In: Journal of Computer Assisted Tomography, Vol. 29, No. 3, 01.05.2005, p. 320-322.

Research output: Contribution to journalArticle

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