Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Diagnosing neurodegenerative diseases, monitoring their progression and assessing responses to treatments will all be aided by the identification of molecular markers of different stages of pathology. Protein biomarkers for HIV-associated neurocognitive disorders that have been discovered using proteomics include complement C3, soluble superoxide dismutase and a prostaglandin synthase. Metabolomics has not yet been widely used for biomarker discovery, but early work shows that it has great potential.

Original languageEnglish (US)
Article number1756
JournalGenome Medicine
Volume2
Issue number3
DOIs
StatePublished - Mar 30 2010

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Metabolomics
Proteomics
Biomarkers
HIV
Human Immunodeficiency Virus Proteins
Complement C3
Prostaglandin-Endoperoxide Synthases
Neurodegenerative Diseases
Superoxide Dismutase
Pathology
Neurocognitive Disorders

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Genetics(clinical)

Cite this

Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders. / Pendyala, Gurudutt N; Fox, Howard S.

In: Genome Medicine, Vol. 2, No. 3, 1756, 30.03.2010.

Research output: Contribution to journalReview article

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