Promises and Prospects of Microbiome Studies

Maria C. Rivera, Jacques Izard

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Next-generation sequencing has transformed genomics and metagenomics. It has contributed to expand our understanding of the complex microbial ecosystems, composed of Archaea, bacteria, viruses, and fungi, populating every habitat on the planet, including the human body. These communities are the metabolic engines driving almost every biochemical reaction on earth. In humans, they provide the enzymatic capability controlling the host physiology. In the next decades, metagenomics will be instrumental in increasing our understanding of the evolution of these complex communities, their functions, and the processes controlling their activities. The application of metagenomics to the human microbiome promises to increase our understanding of the role of the host-microbiome interactions in health, their association with disease state, and the potential to develop therapeutic interventions based on the manipulation of those interactions. This deeper understanding is critical for human survival and the health of the planet.

Original languageEnglish (US)
Title of host publicationMetagenomics for Microbiology
PublisherElsevier Inc.
Pages145-159
Number of pages15
ISBN (Electronic)9780124105089
ISBN (Print)9780124104723
DOIs
StatePublished - Jan 1 2015

Fingerprint

Metagenomics
Microbiota
Planets
Health
Ecosystem
Physiology
Fungi
Viruses
Ecosystems
Bacteria
Earth (planet)
Archaea
Genomics
Engines
Human Body
Survival
Therapeutics

Keywords

  • Biological network
  • Crowdsourced research
  • Ethics
  • Therapeutics
  • Transplants

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Rivera, M. C., & Izard, J. (2015). Promises and Prospects of Microbiome Studies. In Metagenomics for Microbiology (pp. 145-159). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-410472-3.00010-5

Promises and Prospects of Microbiome Studies. / Rivera, Maria C.; Izard, Jacques.

Metagenomics for Microbiology. Elsevier Inc., 2015. p. 145-159.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rivera, MC & Izard, J 2015, Promises and Prospects of Microbiome Studies. in Metagenomics for Microbiology. Elsevier Inc., pp. 145-159. https://doi.org/10.1016/B978-0-12-410472-3.00010-5
Rivera MC, Izard J. Promises and Prospects of Microbiome Studies. In Metagenomics for Microbiology. Elsevier Inc. 2015. p. 145-159 https://doi.org/10.1016/B978-0-12-410472-3.00010-5
Rivera, Maria C. ; Izard, Jacques. / Promises and Prospects of Microbiome Studies. Metagenomics for Microbiology. Elsevier Inc., 2015. pp. 145-159
@inbook{5f9f5f2447f94bdda752364412a361c8,
title = "Promises and Prospects of Microbiome Studies",
abstract = "Next-generation sequencing has transformed genomics and metagenomics. It has contributed to expand our understanding of the complex microbial ecosystems, composed of Archaea, bacteria, viruses, and fungi, populating every habitat on the planet, including the human body. These communities are the metabolic engines driving almost every biochemical reaction on earth. In humans, they provide the enzymatic capability controlling the host physiology. In the next decades, metagenomics will be instrumental in increasing our understanding of the evolution of these complex communities, their functions, and the processes controlling their activities. The application of metagenomics to the human microbiome promises to increase our understanding of the role of the host-microbiome interactions in health, their association with disease state, and the potential to develop therapeutic interventions based on the manipulation of those interactions. This deeper understanding is critical for human survival and the health of the planet.",
keywords = "Biological network, Crowdsourced research, Ethics, Therapeutics, Transplants",
author = "Rivera, {Maria C.} and Jacques Izard",
year = "2015",
month = "1",
day = "1",
doi = "10.1016/B978-0-12-410472-3.00010-5",
language = "English (US)",
isbn = "9780124104723",
pages = "145--159",
booktitle = "Metagenomics for Microbiology",
publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Promises and Prospects of Microbiome Studies

AU - Rivera, Maria C.

AU - Izard, Jacques

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Next-generation sequencing has transformed genomics and metagenomics. It has contributed to expand our understanding of the complex microbial ecosystems, composed of Archaea, bacteria, viruses, and fungi, populating every habitat on the planet, including the human body. These communities are the metabolic engines driving almost every biochemical reaction on earth. In humans, they provide the enzymatic capability controlling the host physiology. In the next decades, metagenomics will be instrumental in increasing our understanding of the evolution of these complex communities, their functions, and the processes controlling their activities. The application of metagenomics to the human microbiome promises to increase our understanding of the role of the host-microbiome interactions in health, their association with disease state, and the potential to develop therapeutic interventions based on the manipulation of those interactions. This deeper understanding is critical for human survival and the health of the planet.

AB - Next-generation sequencing has transformed genomics and metagenomics. It has contributed to expand our understanding of the complex microbial ecosystems, composed of Archaea, bacteria, viruses, and fungi, populating every habitat on the planet, including the human body. These communities are the metabolic engines driving almost every biochemical reaction on earth. In humans, they provide the enzymatic capability controlling the host physiology. In the next decades, metagenomics will be instrumental in increasing our understanding of the evolution of these complex communities, their functions, and the processes controlling their activities. The application of metagenomics to the human microbiome promises to increase our understanding of the role of the host-microbiome interactions in health, their association with disease state, and the potential to develop therapeutic interventions based on the manipulation of those interactions. This deeper understanding is critical for human survival and the health of the planet.

KW - Biological network

KW - Crowdsourced research

KW - Ethics

KW - Therapeutics

KW - Transplants

UR - http://www.scopus.com/inward/record.url?scp=84942606285&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942606285&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-410472-3.00010-5

DO - 10.1016/B978-0-12-410472-3.00010-5

M3 - Chapter

AN - SCOPUS:84942606285

SN - 9780124104723

SP - 145

EP - 159

BT - Metagenomics for Microbiology

PB - Elsevier Inc.

ER -