Primary melanoma of the sphenoid sinus presenting with a third cranial nerve palsy

Shannon C. Lynch, Andrew G. Lee, Scott M. Graham, Patricia A. Kirby

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

An 83-year-old woman presented with right trigeminal paresthesias, upper lid ptosis, and diplopia and was found to have a right third cranial nerve palsy. MRI disclosed a right sphenocavernous mass with speckled high signal on pre-contrast T1 and correspondingly low signal on T2. Endoscopic sphenoidotomy revealed malignant melanoma. The patient underwent radiation therapy with complete and protracted resolution of the palsy. An extensive evaluation for a primary source was negative. The combination of high T1 signal and low T2 signal in a mass should suggest melanin. An exceedingly rare condition, this is the first English report of its presentation with a third cranial nerve palsy.

Original languageEnglish (US)
Pages (from-to)289-292
Number of pages4
JournalJournal of Neuro-Ophthalmology
Volume25
Issue number4
DOIs
StatePublished - Dec 1 2005

Fingerprint

Oculomotor Nerve Diseases
Oculomotor Nerve
Sphenoid Sinus
Cranial Nerve Diseases
Melanoma
Diplopia
Paresthesia
Melanins
Paralysis
Radiotherapy

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

Cite this

Primary melanoma of the sphenoid sinus presenting with a third cranial nerve palsy. / Lynch, Shannon C.; Lee, Andrew G.; Graham, Scott M.; Kirby, Patricia A.

In: Journal of Neuro-Ophthalmology, Vol. 25, No. 4, 01.12.2005, p. 289-292.

Research output: Contribution to journalArticle

Lynch, Shannon C. ; Lee, Andrew G. ; Graham, Scott M. ; Kirby, Patricia A. / Primary melanoma of the sphenoid sinus presenting with a third cranial nerve palsy. In: Journal of Neuro-Ophthalmology. 2005 ; Vol. 25, No. 4. pp. 289-292.
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