Primary follicular lymphoma of the testis in children and adolescents

Mark A. Lones, Martine Raphael, Keith McCarthy, Andrew Wotherspoon, Marie Josee Terrier-Lacombe, Alan D. Ramsay, Ken MacLennan, Mitchell S. Cairo, Mary Gerrard, Jean Michon, Catherine Patte, Ross Pinkerton, Leonard Sender, Anne Auperin, Richard Sposto, Claire Weston, Nyla A. Heerema, Warren G Sanger, Daniel Von Allmen, Sherrie L. Perkins

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100% (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.

Original languageEnglish (US)
Pages (from-to)68-71
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Volume34
Issue number1
DOIs
StatePublished - Jan 1 2012

Fingerprint

Follicular Lymphoma
Testis
Vincristine
Prednisone
Doxorubicin
Cyclophosphamide
Disease-Free Survival
Drug Therapy
Therapeutics

Keywords

  • adolescence
  • child
  • lymphoma B-cell
  • lymphoma follicular
  • testis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

Lones, M. A., Raphael, M., McCarthy, K., Wotherspoon, A., Terrier-Lacombe, M. J., Ramsay, A. D., ... Perkins, S. L. (2012). Primary follicular lymphoma of the testis in children and adolescents. Journal of Pediatric Hematology/Oncology, 34(1), 68-71. https://doi.org/10.1097/MPH.0b013e31820e4636

Primary follicular lymphoma of the testis in children and adolescents. / Lones, Mark A.; Raphael, Martine; McCarthy, Keith; Wotherspoon, Andrew; Terrier-Lacombe, Marie Josee; Ramsay, Alan D.; MacLennan, Ken; Cairo, Mitchell S.; Gerrard, Mary; Michon, Jean; Patte, Catherine; Pinkerton, Ross; Sender, Leonard; Auperin, Anne; Sposto, Richard; Weston, Claire; Heerema, Nyla A.; Sanger, Warren G; Von Allmen, Daniel; Perkins, Sherrie L.

In: Journal of Pediatric Hematology/Oncology, Vol. 34, No. 1, 01.01.2012, p. 68-71.

Research output: Contribution to journalArticle

Lones, MA, Raphael, M, McCarthy, K, Wotherspoon, A, Terrier-Lacombe, MJ, Ramsay, AD, MacLennan, K, Cairo, MS, Gerrard, M, Michon, J, Patte, C, Pinkerton, R, Sender, L, Auperin, A, Sposto, R, Weston, C, Heerema, NA, Sanger, WG, Von Allmen, D & Perkins, SL 2012, 'Primary follicular lymphoma of the testis in children and adolescents', Journal of Pediatric Hematology/Oncology, vol. 34, no. 1, pp. 68-71. https://doi.org/10.1097/MPH.0b013e31820e4636
Lones MA, Raphael M, McCarthy K, Wotherspoon A, Terrier-Lacombe MJ, Ramsay AD et al. Primary follicular lymphoma of the testis in children and adolescents. Journal of Pediatric Hematology/Oncology. 2012 Jan 1;34(1):68-71. https://doi.org/10.1097/MPH.0b013e31820e4636
Lones, Mark A. ; Raphael, Martine ; McCarthy, Keith ; Wotherspoon, Andrew ; Terrier-Lacombe, Marie Josee ; Ramsay, Alan D. ; MacLennan, Ken ; Cairo, Mitchell S. ; Gerrard, Mary ; Michon, Jean ; Patte, Catherine ; Pinkerton, Ross ; Sender, Leonard ; Auperin, Anne ; Sposto, Richard ; Weston, Claire ; Heerema, Nyla A. ; Sanger, Warren G ; Von Allmen, Daniel ; Perkins, Sherrie L. / Primary follicular lymphoma of the testis in children and adolescents. In: Journal of Pediatric Hematology/Oncology. 2012 ; Vol. 34, No. 1. pp. 68-71.
@article{4bcef2bf817c4bb6b1491e3caffb5cfe,
title = "Primary follicular lymphoma of the testis in children and adolescents",
abstract = "This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100{\%} (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.",
keywords = "adolescence, child, lymphoma B-cell, lymphoma follicular, testis",
author = "Lones, {Mark A.} and Martine Raphael and Keith McCarthy and Andrew Wotherspoon and Terrier-Lacombe, {Marie Josee} and Ramsay, {Alan D.} and Ken MacLennan and Cairo, {Mitchell S.} and Mary Gerrard and Jean Michon and Catherine Patte and Ross Pinkerton and Leonard Sender and Anne Auperin and Richard Sposto and Claire Weston and Heerema, {Nyla A.} and Sanger, {Warren G} and {Von Allmen}, Daniel and Perkins, {Sherrie L.}",
year = "2012",
month = "1",
day = "1",
doi = "10.1097/MPH.0b013e31820e4636",
language = "English (US)",
volume = "34",
pages = "68--71",
journal = "Journal of Pediatric Hematology/Oncology",
issn = "1077-4114",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Primary follicular lymphoma of the testis in children and adolescents

AU - Lones, Mark A.

AU - Raphael, Martine

AU - McCarthy, Keith

AU - Wotherspoon, Andrew

AU - Terrier-Lacombe, Marie Josee

AU - Ramsay, Alan D.

AU - MacLennan, Ken

AU - Cairo, Mitchell S.

AU - Gerrard, Mary

AU - Michon, Jean

AU - Patte, Catherine

AU - Pinkerton, Ross

AU - Sender, Leonard

AU - Auperin, Anne

AU - Sposto, Richard

AU - Weston, Claire

AU - Heerema, Nyla A.

AU - Sanger, Warren G

AU - Von Allmen, Daniel

AU - Perkins, Sherrie L.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100% (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.

AB - This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100% (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.

KW - adolescence

KW - child

KW - lymphoma B-cell

KW - lymphoma follicular

KW - testis

UR - http://www.scopus.com/inward/record.url?scp=84855442137&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84855442137&partnerID=8YFLogxK

U2 - 10.1097/MPH.0b013e31820e4636

DO - 10.1097/MPH.0b013e31820e4636

M3 - Article

VL - 34

SP - 68

EP - 71

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

SN - 1077-4114

IS - 1

ER -