Primary extramedullary plasmacytoma in the atria of the heart

Xiaoying Wan, Stefano Tarantolo, Donald F. Orton, Timothy Charles Greiner

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A rare case of primary extramedullary plasmacytoma of the heart is described. The large space-occupying tumor in the atrial wall and its associated significant pericardial effusion caused marked impairment of cardiovascular function. The diagnosis was made via intravenous biopsy. Immunohistochemistry demonstrated CD45 and kappa light chain expression. Other B-cell- and T-cell-specific lymphoid markers were negative. Elevated kappa light chain was detected in serum by immunofixation electrophoresis. The differential diagnosis of plasmacytoma should be considered in cardiac tumors when routine screening is negative with lymphoid (CD20, CD3) and soft tissue immunohistochemical markers.

Original languageEnglish (US)
Pages (from-to)137-139
Number of pages3
JournalCardiovascular Pathology
Volume10
Issue number3
DOIs
StatePublished - Aug 8 2001

Fingerprint

Plasmacytoma
Heart Atria
Light
Heart Neoplasms
Pericardial Effusion
Electrophoresis
Differential Diagnosis
B-Lymphocytes
Immunohistochemistry
T-Lymphocytes
Biopsy
Serum
Neoplasms

Keywords

  • Heart
  • Immunohistochemistry
  • Plasmacytoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Primary extramedullary plasmacytoma in the atria of the heart. / Wan, Xiaoying; Tarantolo, Stefano; Orton, Donald F.; Greiner, Timothy Charles.

In: Cardiovascular Pathology, Vol. 10, No. 3, 08.08.2001, p. 137-139.

Research output: Contribution to journalArticle

Wan, Xiaoying ; Tarantolo, Stefano ; Orton, Donald F. ; Greiner, Timothy Charles. / Primary extramedullary plasmacytoma in the atria of the heart. In: Cardiovascular Pathology. 2001 ; Vol. 10, No. 3. pp. 137-139.
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