Primary central nervous system vasculitis with optic nerve involvement

Christy E. Benson, Alexander Knezevic, Shannon C Lynch

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 20-year-old woman presented with headache, decreased vision, eye pain, and urinary retention. During her clinical course, visual acuity declined to 20/800, right eye, and 20/50, left eye, associated with bilateral optic disc edema. Brain magnetic resonance imaging revealed enhancement of the leptomeninges, right optic nerve, and right side of the optic chiasm. Extensive evaluation of the central nervous system (CNS) for an infectious cause was negative. Brain biopsy showed a pattern consistent with vasculitis. The patient was treated with prednisone and cyclophosphamide, resulting in improvement of her vision and systemic symptoms. Primary CNS vasculitis is a rare condition that may affect the anterior visual pathways.

Original languageEnglish (US)
Pages (from-to)174-177
Number of pages4
JournalJournal of Neuro-Ophthalmology
Volume36
Issue number2
DOIs
StatePublished - Jan 1 2016

Fingerprint

Central Nervous System Vasculitis
Optic Nerve
Eye Pain
Optic Chiasm
Papilledema
Visual Pathways
Urinary Retention
Brain
Vasculitis
Prednisone
Cyclophosphamide
Visual Acuity
Headache
Central Nervous System
Magnetic Resonance Imaging
Biopsy

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

Cite this

Primary central nervous system vasculitis with optic nerve involvement. / Benson, Christy E.; Knezevic, Alexander; Lynch, Shannon C.

In: Journal of Neuro-Ophthalmology, Vol. 36, No. 2, 01.01.2016, p. 174-177.

Research output: Contribution to journalArticle

Benson, Christy E. ; Knezevic, Alexander ; Lynch, Shannon C. / Primary central nervous system vasculitis with optic nerve involvement. In: Journal of Neuro-Ophthalmology. 2016 ; Vol. 36, No. 2. pp. 174-177.
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