Preparation of core/shell PVP/PLA ultrafine fibers by coaxial electrospinning

Bin Sun, Bin Duan, Xiaoyan Yuan

Research output: Contribution to journalArticle

72 Scopus citations

Abstract

This study investigated the process feasibility and stability of core/shell structured bicomponent ultrafine fibers of poly(vinyl pyrrolidone) (PVP) and poly(D,L-lactide) (PLA) by coaxial electrospinning. The morphological structure of the core/shell ultrafine fibers was studied by means of scanning electron microscopy, transmission electron microscopy, and X-ray photoelectron spectroscopy. Results suggested that PVP/PL A core/shell ultrafine fibers with drawbacks could be produced from 6 or 8% PVP solutions (inner) in the mixture of N,N-dimethlformamide (DMF) and ethanol and a 22% PLA solution (outer) in DMF and acetone when the flow rates of inner and outer fluids were 0.05 and 0.1 mL/h, respectively. The tensile modulus and tensile strength of the core/shell PVP/PLA membrane were dramatically lower than those of the electrospun PLA membrane, and its water uptake was twice more than that of the PLA membrane. Membranes made from the biodegradable core/shell ultrafine fibers could be potentially used in loading bioactive molecules for tissue regeneration.

Original languageEnglish (US)
Pages (from-to)39-45
Number of pages7
JournalJournal of Applied Polymer Science
Volume102
Issue number1
DOIs
StatePublished - Oct 5 2006

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Keywords

  • Coaxial electrospinning
  • Core/shell
  • Poly(D,L-lactide)
  • Poly(vinyl pyrrolidone)
  • Ultrafine fiber

ASJC Scopus subject areas

  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Polymers and Plastics
  • Materials Chemistry

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