Predictors of knee joint loading after anterior cruciate ligament reconstruction

Elizabeth A Wellsandt, Ashutosh Khandha, Kurt Manal, Michael J. Axe, Thomas S. Buchanan, Lynn Snyder-Mackler

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Anterior cruciate ligament (ACL) injury results in altered knee joint mechanics which frequently continue even after ACL reconstruction. The persistence of altered mechanical loading of the knee is of concern due to its likely role in the development of post-traumatic osteoarthritis (OA). Joint contact forces are associated with post-traumatic OA development, but evaluation of factors influencing the magnitude of contact forces after ACL injury is needed to advance current strategies aimed at preventing post-traumatic OA. Therefore, the purpose of this study was to identify predictive factors of knee joint contact forces after ACL reconstruction. Thirty athletes completed standard gait analysis with surface electromyography 6 months after ACL reconstruction. An electromyographic-driven musculoskeletal model was used to estimate joint contact forces. External knee adduction moment was a significant predictor of medial compartment contact forces in both limbs, while vertical ground reaction force and co-contraction only contributed significantly in the uninvolved limb. The large influence of the knee adduction moment on joint contact forces provides mechanistic clues to understanding the mechanical pathway of post-traumatic OA after ACL injury. Statement of Clinical Significance: This study provides critical information in improving the understanding of mechanisms influencing the development of post-traumatic OA after ACL injury. Further work is needed to identify additional driving factors of joint loading in the ACL-injured limb and develop treatment strategies to avert the deleterious consequences of post-traumatic OA.

Original languageEnglish (US)
Pages (from-to)651-656
Number of pages6
JournalJournal of Orthopaedic Research
Volume35
Issue number3
DOIs
StatePublished - Mar 1 2017

Fingerprint

Anterior Cruciate Ligament Reconstruction
Knee Joint
Osteoarthritis
Joints
Knee
Extremities
Anterior Cruciate Ligament
Electromyography
Mechanics
Gait
Athletes
Anterior Cruciate Ligament Injuries

Keywords

  • ACL
  • OA
  • cartilage
  • contact force
  • gait

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Predictors of knee joint loading after anterior cruciate ligament reconstruction. / Wellsandt, Elizabeth A; Khandha, Ashutosh; Manal, Kurt; Axe, Michael J.; Buchanan, Thomas S.; Snyder-Mackler, Lynn.

In: Journal of Orthopaedic Research, Vol. 35, No. 3, 01.03.2017, p. 651-656.

Research output: Contribution to journalArticle

Wellsandt, EA, Khandha, A, Manal, K, Axe, MJ, Buchanan, TS & Snyder-Mackler, L 2017, 'Predictors of knee joint loading after anterior cruciate ligament reconstruction', Journal of Orthopaedic Research, vol. 35, no. 3, pp. 651-656. https://doi.org/10.1002/jor.23408
Wellsandt, Elizabeth A ; Khandha, Ashutosh ; Manal, Kurt ; Axe, Michael J. ; Buchanan, Thomas S. ; Snyder-Mackler, Lynn. / Predictors of knee joint loading after anterior cruciate ligament reconstruction. In: Journal of Orthopaedic Research. 2017 ; Vol. 35, No. 3. pp. 651-656.
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