Postterm closure of the cavum septi pellucidi and developmental outcome in premature infants

Howard Needelman, Bruce Schroeder, Matthew Sweeney, John Schmidt, John B. Bodensteiner, G. B. Schaefer

Research output: Contribution to journalArticle

1 Scopus citations


The authors report the natural history of closure of the cavum Septi pellucidi in premature infants 26 to 27 weeks postconception at birth and compare the developmental outcome in these infants who had closure by 42 weeks postconception to those who still had a cavum septum pellucidi visualized on ultrasound at approximately term (35-42 weeks). Of 72 patients, 35 patients still had a cavum septum pellucidi visualized on the last ultrasound done between 35 and 42 weeks postconception, and the developmental outcome of these patients was no different from those with earlier closure. The authors conclude that persistence of a cavum septi pellucidi through term is not an independent risk factor for developmental delay.

Original languageEnglish (US)
Pages (from-to)314-316
Number of pages3
JournalJournal of Child Neurology
Issue number3
StatePublished - Mar 1 2007



  • Brain development
  • Developmental outcome
  • Midline brain anomalies
  • Septum Pellucidum

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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