Polychlorinated biphenyl contamination and minisatellite DNA mutation rates of tree swallows

Mary Stapleton, Peter O. Dunn, John McCarty, Anne Secord, Linda A. Whittingham

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The evidence that exposure to polychlorinated biphenyls (PCBs) leads to mutations is equivocal and controversial. Using multilocus DNA fingerprinting, we compared the mutation rate of tree swallows (Tachycineta bicolor) nesting at sites with high and low levels of contamination with PCBs. The upper Hudson River, USA, is highly contaminated with PCBs as a result of releases from two capacitor manufacturing plants in Hudson Falls and Fort Edward, New York, USA. Tree swallows nesting nearby have some of the highest known concentrations of PCBs in their tissues of any contemporary bird population (up to 114, 000 ng PCB/g tissue). We found no difference in mutation rates between sites in New York with high PCB contamination and reference sites in Wisconsin, USA, and Ontario and Alberta, Canada, with known or presumably low levels of. contamination. Thus, the mechanism behind altered reproductive behavior of tree swallows along the upper Hudson River is most likely physiological impairment, such as endocrine disruption, rather than mutation.

Original languageEnglish (US)
Pages (from-to)2263-2267
Number of pages5
JournalEnvironmental Toxicology and Chemistry
Volume20
Issue number10
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

Fingerprint

DNA Contamination
Swallows
Minisatellite Repeats
Polychlorinated Biphenyls
Mutation Rate
mutation
PCB
Contamination
DNA
Rivers
Tissue
Reproductive Behavior
DNA fingerprinting
Alberta
Mutation
DNA Fingerprinting
reproductive behavior
Birds
Ontario
river

Keywords

  • Hudson river
  • Mutation rate
  • Polychlorinated biphenyls
  • Tree swallow

ASJC Scopus subject areas

  • Environmental Chemistry
  • Health, Toxicology and Mutagenesis

Cite this

Polychlorinated biphenyl contamination and minisatellite DNA mutation rates of tree swallows. / Stapleton, Mary; Dunn, Peter O.; McCarty, John; Secord, Anne; Whittingham, Linda A.

In: Environmental Toxicology and Chemistry, Vol. 20, No. 10, 01.01.2001, p. 2263-2267.

Research output: Contribution to journalArticle

Stapleton, Mary ; Dunn, Peter O. ; McCarty, John ; Secord, Anne ; Whittingham, Linda A. / Polychlorinated biphenyl contamination and minisatellite DNA mutation rates of tree swallows. In: Environmental Toxicology and Chemistry. 2001 ; Vol. 20, No. 10. pp. 2263-2267.
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