Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA

Marie Feser, Lezlie A. Derber, Kevin D. Deane, Dennis C. Lezotte, Michael H. Weisman, Jane H. Buckner, Ted R Mikuls, James Robert O'Dell, Peter K. Gregersen, V. Michael Holers, Jill M. Norris

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Objective. To evaluate the association between rheumatoid arthritis (RA)-related autoantibodies and plasma 25,OH vitamin D in subjects at risk for RA. Methods. In 1210 subjects without RA, 76 were positive for anti-cyclic citrullinated peptide antibodies or for at least 2 rheumatoid factors (RF; by nephelometry: RF-IgM, RF-IgG, RF-IgA). 25,OH vitamin D was measured in these cases and 154 autoantibody-negative controls from this cohort. Results. 25,OH vitamin D levels did not differ between cases and controls (adjusted OR 1.23, 95% CI 0.93-1.63). Conclusion. Vitamin D concentrations are not associated with RA-related autoimmunity in unaffected subjects at increased risk for RA. The Journal of Rheumatology

Original languageEnglish (US)
Pages (from-to)943-946
Number of pages4
JournalJournal of Rheumatology
Volume36
Issue number5
DOIs
StatePublished - May 1 2009

Fingerprint

Vitamin D
Autoantibodies
Rheumatoid Arthritis
Nephelometry and Turbidimetry
Rheumatoid Factor
Rheumatology
Autoimmunity
Immunoglobulin A
Immunoglobulin M
Immunoglobulin G
Antibodies

Keywords

  • Autoantibodies
  • Rheumatoid arthritis
  • Vitamin D

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Cite this

Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA. / Feser, Marie; Derber, Lezlie A.; Deane, Kevin D.; Lezotte, Dennis C.; Weisman, Michael H.; Buckner, Jane H.; Mikuls, Ted R; O'Dell, James Robert; Gregersen, Peter K.; Holers, V. Michael; Norris, Jill M.

In: Journal of Rheumatology, Vol. 36, No. 5, 01.05.2009, p. 943-946.

Research output: Contribution to journalArticle

Feser, Marie ; Derber, Lezlie A. ; Deane, Kevin D. ; Lezotte, Dennis C. ; Weisman, Michael H. ; Buckner, Jane H. ; Mikuls, Ted R ; O'Dell, James Robert ; Gregersen, Peter K. ; Holers, V. Michael ; Norris, Jill M. / Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA. In: Journal of Rheumatology. 2009 ; Vol. 36, No. 5. pp. 943-946.
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AU - Lezotte, Dennis C.

AU - Weisman, Michael H.

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AU - Norris, Jill M.

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