Physiological role of NBCe2 in the regulation of electrolyte transport in the distal nephron

Donghai Wen, Steven C. Sansom

Research output: Contribution to journalReview article

3 Scopus citations


The electrogenic Na+-HCO3cotransporter 2 (NBCe2) is a newly discovered protein in the distal nephron. Our understanding is minimal regarding its physiological role in renal electrolyte transport. In this mini-review, we summarize the potential function of NBCe2 in the regulation of blood pressure, acid-base, and K+ and Ca2+ transport in the distal nephron.

Original languageEnglish (US)
Pages (from-to)F489-F491
JournalAmerican Journal of Physiology - Renal Physiology
Issue number6
Publication statusPublished - Sep 15 2015



  • Acid-base
  • Ca
  • Hypertension
  • K
  • NBCe2

ASJC Scopus subject areas

  • Physiology
  • Urology

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