Phycodnaviridae - Large DNA algal viruses

James L Van Etten, M. V. Graves, D. G. Müller, W. Boland, N. Delaroque

Research output: Contribution to journalReview article

124 Citations (Scopus)

Abstract

Members and prospective members of the family Phycodnaviridae are large icosahedral, dsDNA (180 to 560 kb) viruses that infect eukaryotic algae. The genomes of two phycodnaviruses have been sequenced: the 331 kb genome of Paramecium bursaria chlorella virus (PBCV-1) and more recently, the 336 kb genome of the Ectocarpus siliculosus virus (EsV-1). EsV-1 has ∼ 231 protein-encoding genes whereas, the slightly smaller PBCV-1 genome has 11 tRNA genes and ∼ 375 protein-encoding genes. Surprisingly, the two viruses only have 33 genes in common, of which 17 have no counterparts in the databases. The low number of homologous genes between the two viruses can probably be attributed to their different life styles. PBCV-1 is a lytic virus that infects a unicellular, endosymbiotic freshwater green alga whereas, EsV-1 is a lysogenic virus that infects a free-living filamentous marine brown alga. Furthermore, accumulating evidence indicates that the phycodnaviruses and their genes are ancient, thus allowing significant differences to have evolved. This review briefly describes some of the biological properties of the phycodnaviruses, focusing on PBCV-1 and EsV-1, and then compares their genomes.

Original languageEnglish (US)
Pages (from-to)1479-1516
Number of pages38
JournalArchives of Virology
Volume147
Issue number8
DOIs
StatePublished - Sep 12 2002

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Phycodnaviridae
DNA Viruses
Viruses
Genome
Genes
Paramecium
Phaeophyta
Chlorella
Chlorophyta
Transfer RNA
Fresh Water
Life Style
Proteins
Databases

ASJC Scopus subject areas

  • Virology

Cite this

Van Etten, J. L., Graves, M. V., Müller, D. G., Boland, W., & Delaroque, N. (2002). Phycodnaviridae - Large DNA algal viruses. Archives of Virology, 147(8), 1479-1516. https://doi.org/10.1007/s00705-002-0822-6

Phycodnaviridae - Large DNA algal viruses. / Van Etten, James L; Graves, M. V.; Müller, D. G.; Boland, W.; Delaroque, N.

In: Archives of Virology, Vol. 147, No. 8, 12.09.2002, p. 1479-1516.

Research output: Contribution to journalReview article

Van Etten, JL, Graves, MV, Müller, DG, Boland, W & Delaroque, N 2002, 'Phycodnaviridae - Large DNA algal viruses', Archives of Virology, vol. 147, no. 8, pp. 1479-1516. https://doi.org/10.1007/s00705-002-0822-6
Van Etten JL, Graves MV, Müller DG, Boland W, Delaroque N. Phycodnaviridae - Large DNA algal viruses. Archives of Virology. 2002 Sep 12;147(8):1479-1516. https://doi.org/10.1007/s00705-002-0822-6
Van Etten, James L ; Graves, M. V. ; Müller, D. G. ; Boland, W. ; Delaroque, N. / Phycodnaviridae - Large DNA algal viruses. In: Archives of Virology. 2002 ; Vol. 147, No. 8. pp. 1479-1516.
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