Phosphinate-containing rhodol and fluorescein scaffolds for the development of bioprobes

Yuan Fang, Gillian N. Good, Xinqi Zhou, Cliff I. Stains

Research output: Contribution to journalArticle

4 Scopus citations


A series of phosphinate-containing rhodol and fluorescein dyes are disclosed. These new fluorophores increase the color palette of phosphinate-based xanthenes in the far-red spectral region. The new chemical functionality of these scaffolds is leveraged to produce a sensitive, no-wash imaging probe for cellular esterase activity. The reported phosphinate-containing dyes provide platforms for the further development of imaging probes and self-reporting delivery vehicles.

Original languageEnglish (US)
Pages (from-to)5962-5965
Number of pages4
JournalChemical Communications
Issue number42
StatePublished - Jan 1 2019


ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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