Phenolsulfonphthalein binding capacity ofserum in newborn infants

Harold M. Maurer, James A. Wolff, Koon Hung Luke

Research output: Contribution to journalArticle

6 Scopus citations


The dye (PSP) binding capacity (D.B.C.) in serum of full-term and premature infantswas investigated. Normal infants and those with hemolytic and nonhemolytic hyperbilirubinemia were studied. Prematurity and hemolytic disease were shown to be factors associated with the greatest reduction in D.B.C. of serum. Infusion of albumin into two premature babies with nonhemolytic hyperbilirubinemia resulted in a rise of D.B.C. with only a transient elevation of bilirubin. The relationship of the D.B.C. to susceptibility to kernicterus in premature and full-term infants with hemolytic and nonhemolytic hyperbilirubinemia is discussed.

Original languageEnglish (US)
Pages (from-to)231-239
Number of pages9
JournalThe Journal of Pediatrics
Issue number2
Publication statusPublished - Feb 1969


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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