Phenacetin abuse and renal pelvic carcinoma

U. Bengtsson, L. Angervall, S. Johansson, L. Wahlgvist

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

This work is a review of 62 patients with abuse of phenacetin containing drugs and uroepithelial tumors of the renal pelvis, all of them carcinomas. Most of the patients had a preexisting nephropathy with papillary necrosis as a prominent feature. Renal impairment contributed to the poor prognosis. On the basis of present knowledge of urinary tract carcinogens and phenacetin metabolites, it is assumed that phenacetin is the crucial factor for development of the tumours.

Original languageEnglish (US)
Pages (from-to)290-294
Number of pages5
JournalInternational Journal of Clinical Pharmacology Therapy and Toxicology
Volume12
Issue number1-2
Publication statusPublished - Dec 1 1975

    Fingerprint

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology (medical)

Cite this

Bengtsson, U., Angervall, L., Johansson, S., & Wahlgvist, L. (1975). Phenacetin abuse and renal pelvic carcinoma. International Journal of Clinical Pharmacology Therapy and Toxicology, 12(1-2), 290-294.