Phenacetin abuse and renal pelvic carcinoma

U. Bengtsson, L. Angervall, S. Johansson, L. Wahlgvist

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This work is a review of 62 patients with abuse of phenacetin containing drugs and uroepithelial tumors of the renal pelvis, all of them carcinomas. Most of the patients had a preexisting nephropathy with papillary necrosis as a prominent feature. Renal impairment contributed to the poor prognosis. On the basis of present knowledge of urinary tract carcinogens and phenacetin metabolites, it is assumed that phenacetin is the crucial factor for development of the tumours.

Original languageEnglish (US)
Pages (from-to)290-294
Number of pages5
JournalInternational Journal of Clinical Pharmacology Therapy and Toxicology
Volume12
Issue number1-2
StatePublished - Dec 1 1975

Fingerprint

Phenacetin
Carcinoma
Kidney
Tumors
Kidney Pelvis
Metabolites
Urinary Tract
Carcinogens
Neoplasms
Necrosis
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology (medical)

Cite this

Bengtsson, U., Angervall, L., Johansson, S., & Wahlgvist, L. (1975). Phenacetin abuse and renal pelvic carcinoma. International Journal of Clinical Pharmacology Therapy and Toxicology, 12(1-2), 290-294.

Phenacetin abuse and renal pelvic carcinoma. / Bengtsson, U.; Angervall, L.; Johansson, S.; Wahlgvist, L.

In: International Journal of Clinical Pharmacology Therapy and Toxicology, Vol. 12, No. 1-2, 01.12.1975, p. 290-294.

Research output: Contribution to journalArticle

Bengtsson, U, Angervall, L, Johansson, S & Wahlgvist, L 1975, 'Phenacetin abuse and renal pelvic carcinoma', International Journal of Clinical Pharmacology Therapy and Toxicology, vol. 12, no. 1-2, pp. 290-294.
Bengtsson U, Angervall L, Johansson S, Wahlgvist L. Phenacetin abuse and renal pelvic carcinoma. International Journal of Clinical Pharmacology Therapy and Toxicology. 1975 Dec 1;12(1-2):290-294.
Bengtsson, U. ; Angervall, L. ; Johansson, S. ; Wahlgvist, L. / Phenacetin abuse and renal pelvic carcinoma. In: International Journal of Clinical Pharmacology Therapy and Toxicology. 1975 ; Vol. 12, No. 1-2. pp. 290-294.
@article{370e6bbe20cc43f4b466d58ec8e33d4f,
title = "Phenacetin abuse and renal pelvic carcinoma",
abstract = "This work is a review of 62 patients with abuse of phenacetin containing drugs and uroepithelial tumors of the renal pelvis, all of them carcinomas. Most of the patients had a preexisting nephropathy with papillary necrosis as a prominent feature. Renal impairment contributed to the poor prognosis. On the basis of present knowledge of urinary tract carcinogens and phenacetin metabolites, it is assumed that phenacetin is the crucial factor for development of the tumours.",
author = "U. Bengtsson and L. Angervall and S. Johansson and L. Wahlgvist",
year = "1975",
month = "12",
day = "1",
language = "English (US)",
volume = "12",
pages = "290--294",
journal = "International Journal of Clinical Pharmacology and Therapeutics",
issn = "0946-1965",
publisher = "Dustri-Verlag Dr. Karl Feistle",
number = "1-2",

}

TY - JOUR

T1 - Phenacetin abuse and renal pelvic carcinoma

AU - Bengtsson, U.

AU - Angervall, L.

AU - Johansson, S.

AU - Wahlgvist, L.

PY - 1975/12/1

Y1 - 1975/12/1

N2 - This work is a review of 62 patients with abuse of phenacetin containing drugs and uroepithelial tumors of the renal pelvis, all of them carcinomas. Most of the patients had a preexisting nephropathy with papillary necrosis as a prominent feature. Renal impairment contributed to the poor prognosis. On the basis of present knowledge of urinary tract carcinogens and phenacetin metabolites, it is assumed that phenacetin is the crucial factor for development of the tumours.

AB - This work is a review of 62 patients with abuse of phenacetin containing drugs and uroepithelial tumors of the renal pelvis, all of them carcinomas. Most of the patients had a preexisting nephropathy with papillary necrosis as a prominent feature. Renal impairment contributed to the poor prognosis. On the basis of present knowledge of urinary tract carcinogens and phenacetin metabolites, it is assumed that phenacetin is the crucial factor for development of the tumours.

UR - http://www.scopus.com/inward/record.url?scp=0016710557&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016710557&partnerID=8YFLogxK

M3 - Article

C2 - 1165138

AN - SCOPUS:0016710557

VL - 12

SP - 290

EP - 294

JO - International Journal of Clinical Pharmacology and Therapeutics

JF - International Journal of Clinical Pharmacology and Therapeutics

SN - 0946-1965

IS - 1-2

ER -