Performance of conventional and antimicrobial-treated filtering facepiece respirators challenged with biological aerosols

Michael B. Lore, John M. Sebastian, Teanne L. Brown, Andrew S. Viner, Nicole V. McCullough, Steven Heye Hinrichs

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

This study evaluated the filtration performance of four commercially available models of National Institute of Occupational Safety and Health (NIOSH)-certified filtering facepiece respirators (FFR) against both biological and inert aerosols at a flow rate of 85 L/min. Conventional N95 and P100 FFRs and two antimicrobial (AM)-treated FFRs (an N95 and a P95, both with iodine-based AM treatments) were tested for both physical penetration (PEN P) and viable penetration (PEN V) with three different bioaerosols, including MS2 bacteriophage virus, and the spores and vegetative cells of Bacillus atrophaeus bacteria, in addition to inert sodium chloride (NaCl) aerosol. For each FFR model, the PEN P measured with NaCl was predictive of its MS2 PEN P, and it was observed that spores and bacteria aerosols were also filtered similarly to the inert aerosol. For both conventional FFRs, up to a 1-log reduction in PEN V in comparison with PEN P was observed and attributed to the experimental variability of the test system. For both models of AM-FFRs, no statistically significant differences between PEN V and PEN P for any of the three different bioaerosol challenges were observed. Thus, no bioaerosol filtration enhancement over the conventional FFRs was detected for either iodine-based AM-FFR. In the absence of any standardized test methods, we recommend that future studies evaluating the filtration performance of AM-treated FFRs incorporate the experimental best practices described herein.

Original languageEnglish (US)
Pages (from-to)69-80
Number of pages12
JournalJournal of occupational and environmental hygiene
Volume9
Issue number2
DOIs
StatePublished - Feb 1 2012

Fingerprint

Mechanical Ventilators
Aerosols
Spores
Iodine
Levivirus
National Institute for Occupational Safety and Health (U.S.)
Bacteria
Practice Guidelines
Sodium Chloride
Bacillus
Viruses

Keywords

  • antimicrobial
  • bioaerosol
  • disinfection
  • iodine
  • microbiology
  • respirator

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Performance of conventional and antimicrobial-treated filtering facepiece respirators challenged with biological aerosols. / Lore, Michael B.; Sebastian, John M.; Brown, Teanne L.; Viner, Andrew S.; McCullough, Nicole V.; Hinrichs, Steven Heye.

In: Journal of occupational and environmental hygiene, Vol. 9, No. 2, 01.02.2012, p. 69-80.

Research output: Contribution to journalReview article

Lore, Michael B. ; Sebastian, John M. ; Brown, Teanne L. ; Viner, Andrew S. ; McCullough, Nicole V. ; Hinrichs, Steven Heye. / Performance of conventional and antimicrobial-treated filtering facepiece respirators challenged with biological aerosols. In: Journal of occupational and environmental hygiene. 2012 ; Vol. 9, No. 2. pp. 69-80.
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