Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation

APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD)

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Patients with a Fontan circulation are at risk of a sedentary lifestyle. Given the direct relationship between physical activity and health, promotion of physical activity has the potential to improve outcomes, including quality of life (QOL). This study aimed to describe self-reported physical activity levels in adult Fontan patients and examine associations between physical activity, perceived health status and QOL. The sample consisted of 177 Fontan patients (Mage = 27.5 ± 7.6 years, 52% male)who reported their physical activity, perceived health status, and QOL as part of the cross-sectional Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease – International Study. Descriptive statistics and univariate analyses of variance with planned contrasts were computed to describe physical activity characteristics. Mediation analyses tested whether perceived health status variables mediated the association between physical activity and QOL. Forty-six percent of patients were sedentary while only 40% met international physical activity guidelines. Higher physical activity was associated with younger age, lower NYHA class, higher perceived general health, and greater QOL. Patients who commuted by walking and engaged in sports reported better perceived health and QOL. Mediation analyses revealed that perceived general health but not NYHA functional class mediated the association between physical activity and QOL (αβ = 0.22, 95% confidence interval = 0.04 to 0.49). In conclusion, Fontan patients likely benefit from regular physical activity, having both higher perceived general health and functional capacity; greater perceived health status may contribute to enhanced QOL. In conclusion, these data support the pivotal role of regular physical activity for Fontan patients.

Original languageEnglish (US)
Pages (from-to)144-150
Number of pages7
JournalAmerican Journal of Cardiology
Volume124
Issue number1
DOIs
StatePublished - Jul 1 2019

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Quality of Life
Exercise
Health
Health Status
Sedentary Lifestyle
Health Promotion
Walking
Sports
Heart Diseases
Analysis of Variance
Guidelines
Confidence Intervals

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD) (2019). Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation. American Journal of Cardiology, 124(1), 144-150. https://doi.org/10.1016/j.amjcard.2019.03.039

Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation. / APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).

In: American Journal of Cardiology, Vol. 124, No. 1, 01.07.2019, p. 144-150.

Research output: Contribution to journalArticle

APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD) 2019, 'Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation', American Journal of Cardiology, vol. 124, no. 1, pp. 144-150. https://doi.org/10.1016/j.amjcard.2019.03.039
APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD). Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation. American Journal of Cardiology. 2019 Jul 1;124(1):144-150. https://doi.org/10.1016/j.amjcard.2019.03.039
APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD). / Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation. In: American Journal of Cardiology. 2019 ; Vol. 124, No. 1. pp. 144-150.
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abstract = "Patients with a Fontan circulation are at risk of a sedentary lifestyle. Given the direct relationship between physical activity and health, promotion of physical activity has the potential to improve outcomes, including quality of life (QOL). This study aimed to describe self-reported physical activity levels in adult Fontan patients and examine associations between physical activity, perceived health status and QOL. The sample consisted of 177 Fontan patients (Mage = 27.5 ± 7.6 years, 52{\%} male)who reported their physical activity, perceived health status, and QOL as part of the cross-sectional Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease – International Study. Descriptive statistics and univariate analyses of variance with planned contrasts were computed to describe physical activity characteristics. Mediation analyses tested whether perceived health status variables mediated the association between physical activity and QOL. Forty-six percent of patients were sedentary while only 40{\%} met international physical activity guidelines. Higher physical activity was associated with younger age, lower NYHA class, higher perceived general health, and greater QOL. Patients who commuted by walking and engaged in sports reported better perceived health and QOL. Mediation analyses revealed that perceived general health but not NYHA functional class mediated the association between physical activity and QOL (αβ = 0.22, 95{\%} confidence interval = 0.04 to 0.49). In conclusion, Fontan patients likely benefit from regular physical activity, having both higher perceived general health and functional capacity; greater perceived health status may contribute to enhanced QOL. In conclusion, these data support the pivotal role of regular physical activity for Fontan patients.",
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