Pediatric inflammatory myofibroblastic tumor with late metastasis to the lung: Case report and review of the literature

Raffaella A. Morotti, Michael D. Legman, Nanda Kerkar, Bruce R. Pawel, Warren G. Sanger, Cheryl M. Coffin

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Inflammatory myofibroblastic tumors (IMTs) are challenging lesions with respect to classification, differential diagnosis, and biologic potential. In children, extrapulmonary IMTs, particularly those from the abdomen or mesentery, are generally aggressive, with frequent local recurrences. There are few documented patients with distant metastasis, and most of these had metastases at presentation or developed metastases within months to a few years. We add to the short list of metastatic extrapulmonary IMTs a pediatric patient in whom the primary lesion was widespread in the abdomen at presentation and metastatic disease to the lung was diagnosed 9 years after the primary resection. We describe the clinical and pathologic features of this patient and review the characteristics of extrapulmonary IMTs with distant metastasis reported in the literature.

Original languageEnglish (US)
Pages (from-to)224-229
Number of pages6
JournalPediatric and Developmental Pathology
Volume8
Issue number2
DOIs
StatePublished - Apr 1 2005

Fingerprint

Pediatrics
Neoplasm Metastasis
Lung
Abdomen
Neoplasms
Mesentery
Lung Diseases
Differential Diagnosis
Recurrence

Keywords

  • Children
  • Extrapulmonary inflammatory myofibroblastic tumor
  • Inflammatory fibrosarcoma
  • Inflammatory myofibroblastic tumor
  • Metastasis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

Cite this

Pediatric inflammatory myofibroblastic tumor with late metastasis to the lung : Case report and review of the literature. / Morotti, Raffaella A.; Legman, Michael D.; Kerkar, Nanda; Pawel, Bruce R.; Sanger, Warren G.; Coffin, Cheryl M.

In: Pediatric and Developmental Pathology, Vol. 8, No. 2, 01.04.2005, p. 224-229.

Research output: Contribution to journalArticle

Morotti, Raffaella A. ; Legman, Michael D. ; Kerkar, Nanda ; Pawel, Bruce R. ; Sanger, Warren G. ; Coffin, Cheryl M. / Pediatric inflammatory myofibroblastic tumor with late metastasis to the lung : Case report and review of the literature. In: Pediatric and Developmental Pathology. 2005 ; Vol. 8, No. 2. pp. 224-229.
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