Abstract
The pathogenicity of three isolates of porcine respiratory coronavirus (AR310, LEPP and 1894) from the USA was assessed in specific pathogen-free pigs. Pigs inoculated with 1894 developed mild respiratory disease and pigs inoculated with AR310 and LEPP developed moderate respiratory disease from fout to 10 days after they were inoculated, but all the pigs recovered fully by 14 days after inoculation. Gross and microscopic examination revealed mild (1894) to moderate (AR310 and LEPP) multifocal bronchointerstitial pneumonia from four to 10 days after inoculation. The lesions were characterised by necrotising bronchiolitis, septal infiltration with mononuclear cells, and a mixed alveolar exudate. No clinical signs or microscopic lesions were observed in cotnrol pigs that had not been inoculated.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 358-361 |
| Number of pages | 4 |
| Journal | Veterinary Record |
| Volume | 152 |
| Issue number | 12 |
| DOIs | |
| State | Published - Mar 22 2003 |
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Pathogenicity of three isolates of porcine respiratory coronavirus in the USA. / Halbur, P. G.; Pallarés, F. J.; Opriessnig, T.; Vaughn, E. M.; Paul, P. S.
In: Veterinary Record, Vol. 152, No. 12, 22.03.2003, p. 358-361.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pathogenicity of three isolates of porcine respiratory coronavirus in the USA
AU - Halbur, P. G.
AU - Pallarés, F. J.
AU - Opriessnig, T.
AU - Vaughn, E. M.
AU - Paul, P. S.
PY - 2003/3/22
Y1 - 2003/3/22
N2 - The pathogenicity of three isolates of porcine respiratory coronavirus (AR310, LEPP and 1894) from the USA was assessed in specific pathogen-free pigs. Pigs inoculated with 1894 developed mild respiratory disease and pigs inoculated with AR310 and LEPP developed moderate respiratory disease from fout to 10 days after they were inoculated, but all the pigs recovered fully by 14 days after inoculation. Gross and microscopic examination revealed mild (1894) to moderate (AR310 and LEPP) multifocal bronchointerstitial pneumonia from four to 10 days after inoculation. The lesions were characterised by necrotising bronchiolitis, septal infiltration with mononuclear cells, and a mixed alveolar exudate. No clinical signs or microscopic lesions were observed in cotnrol pigs that had not been inoculated.
AB - The pathogenicity of three isolates of porcine respiratory coronavirus (AR310, LEPP and 1894) from the USA was assessed in specific pathogen-free pigs. Pigs inoculated with 1894 developed mild respiratory disease and pigs inoculated with AR310 and LEPP developed moderate respiratory disease from fout to 10 days after they were inoculated, but all the pigs recovered fully by 14 days after inoculation. Gross and microscopic examination revealed mild (1894) to moderate (AR310 and LEPP) multifocal bronchointerstitial pneumonia from four to 10 days after inoculation. The lesions were characterised by necrotising bronchiolitis, septal infiltration with mononuclear cells, and a mixed alveolar exudate. No clinical signs or microscopic lesions were observed in cotnrol pigs that had not been inoculated.
UR - http://www.scopus.com/inward/record.url?scp=0344838446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0344838446&partnerID=8YFLogxK
U2 - 10.1136/vr.152.12.358
DO - 10.1136/vr.152.12.358
M3 - Article
C2 - 12678259
AN - SCOPUS:0344838446
VL - 152
SP - 358
EP - 361
JO - Veterinary Record
JF - Veterinary Record
SN - 0042-4900
IS - 12
ER -